2-CHLORO-3-NITROPYRIDINE - Names and Identifiers
2-CHLORO-3-NITROPYRIDINE - Physico-chemical Properties
Molecular Formula | C5H3ClN2O2
|
Molar Mass | 158.54 |
Melting Point | 100-103°C(lit.) |
Flash Point | 185 °C |
Appearance | Yellow crystal |
Storage Condition | Room Temprature |
Refractive Index | 1.454-1.456 |
MDL | MFCD00006232 |
Physical and Chemical Properties | Melting Point: 100-102°C refractive index: 456 flash point: 185°C
|
Use | Pharmaceutical intermediates. |
2-CHLORO-3-NITROPYRIDINE - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 20/22 - Harmful by inhalation and if swallowed.
|
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
UN IDs | UN 2811 |
WGK Germany | 3 |
2-CHLORO-3-NITROPYRIDINE - Introduction
2-Chloro-3-nitropyridine is an organic compound with the chemical formula C5H3ClN2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal
-melting point: 82-84 ℃
-Boiling point: 274-276 ℃
-Density: 1.62g/cm3
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.
Use:
- 2-Chloro-3-nitropyridine can be used as organic synthesis intermediates, widely used in pesticides, pharmaceuticals and dyes and other fields.
-In pesticides, it is often used as a raw material for insecticides and fungicides.
-In the field of medicine, it can be used to synthesize antibiotics and other drug intermediates.
-In addition, 2-Chloro-3-nitropyridine can also be used as catalysts and catalytic reagents in organic synthesis reactions.
Preparation Method:
- 2-Chloro-3-nitropyridine can be obtained by reacting pyridine with chlorine and nitric acid. The reaction is generally carried out under the protection of inert gas, and the reaction temperature and reaction time will affect the yield and purity of the product.
Safety Information:
- 2-Chloro-3-nitropyridine has a certain risk, please comply with the relevant safety operation specifications.
-Avoid contact with skin and eyes during operation, and pay attention to personal protective measures, such as wearing gloves, goggles and protective clothing.
-The compound should be stored in a dry, cool, well-ventilated place, and away from fire and flammable materials.
-Observe national and regional laws and regulations when handling the substance.
Last Update:2024-04-09 20:52:54