2-CHLORO-4,6-DIMETHYLNICOTINONITRILE
2-Chloro-3-cyano-4,6-dimethylpyridine
CAS: 14237-71-9
Molecular Formula: C8H7ClN2
2-CHLORO-4,6-DIMETHYLNICOTINONITRILE - Names and Identifiers
| Name | 2-Chloro-3-cyano-4,6-dimethylpyridine |
| Synonyms | AKOS BC-3128 AKOS BBS-00002510 IFLAB-BB F1371-0162 2-CHLORO-4,6-DIMETHYLNICOTINONITRILE 2-CHLORO-3-CYANO-4,6-DIMETHYLPYRIDINE 2-Chloro-3-cyano-4,6-dimethylpyridine 2-chloro-4,6-dimethylpyridine-3-carbonitrile 2-CHLORO-4,6-DIMETHYL-3-PYRIDINECARBONITRILE |
| CAS | 14237-71-9 |
| InChI | InChI=1/C8H7ClN2/c1-5-3-6(2)11-8(9)7(5)4-10/h3H,1-2H3 |
2-CHLORO-4,6-DIMETHYLNICOTINONITRILE - Physico-chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molar Mass | 166.61 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Melting Point | 98-99°C |
| Boling Point | 305.3±37.0 °C(Predicted) |
| Flash Point | 138.5°C |
| Vapor Presure | 0.000827mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 131348 |
| pKa | -0.41±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.546 |
2-CHLORO-4,6-DIMETHYLNICOTINONITRILE - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R25 - Toxic if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3276 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
2-CHLORO-4,6-DIMETHYLNICOTINONITRILE - Introduction
1. nature:
2-Chloro-3-cyano-4, 6-lutidine is an organic compound with the appearance of a colorless crystalline solid. It has low solubility and is soluble in organic solvents such as ethanol and dichloromethane. It is stable in air, but decomposes when heated.
2. use:
2-Chloro-3-cyano-4, 6-lutidine has certain bactericidal and antibacterial activity. It is commonly used as an insecticide and fungicide in agriculture to control diseases and pests on crops. In addition, it can also be used to synthesize other compounds, and has certain application value in the field of pharmaceutical synthesis and organic synthesis.
3. Preparation method:
The preparation method of 2-chloro-3-cyano-4, 6-lutidine is generally obtained by reacting piperidine with chlorocyanate under alkaline conditions. The specific synthesis process is as follows:
First, piperidine is reacted with chlorocyanate under alkaline conditions to produce 2-chloro-3-cyano-4, 6-lutidine. The reaction can be carried out under anhydrous and anaerobic conditions to avoid side reactions. Subsequently, the target product is purified by distillation, crystallization, or the like.
4. Safety Information:
2-chloro -3-cyano -4,6-lutidine in the operation and storage need to pay attention to the following safety matters:
-Avoid contact with skin and eyes to avoid irritation or discomfort. Appropriate personal protective equipment, such as gloves, protective glasses and face shields, should be worn during operation.
-Avoid inhaling its particles or gas, as it may cause damage to the respiratory system. During the operation, it should be maintained in a well-ventilated condition or under a protective cover.
-During storage and handling, it needs to be isolated from flammable substances and oxidants to prevent unsafe chemical reactions.
-In the event of ingestion or inhalation, seek medical attention immediately and bring the relevant packaging or its label.
Last Update：2024-04-09 21:01:54
