2-CHLORO-4-HYDROXYMETHYLPYRIDINE

2-CHLORO-4-HYDROXYMETHYLPYRIDINE - Names and Identifiers

Name	(2-CHLORO-PYRIDIN-4-YL)-METHANOL
Synonyms	BUTTPARK 15450-15 2-Chloro-4-pyridinemethanol 4-Pyridinemethanol, 2-chloro- (2-CHLORO-4-PYRIDINYL)METHANOL (2-CHLORO-PYRIDIN-4-YL)-METHANOL 2-CHLORO-4-HYDROXYMETHYLPYRIDINE (2-CHLORO-PYRIDINE-4-YL)-METHANOL 2-Chloro-4-(hydroxymethyl)pyridine 4-Pyridinemethanol,2-chloro-(6CI,9CI)
CAS	100704-10-7
EINECS	680-968-4
InChI	InChI=1/C7H8INO/c1-2-10-7-6(8)4-3-5-9-7/h3-5H,2H2,1H3

2-CHLORO-4-HYDROXYMETHYLPYRIDINE - Physico-chemical Properties

Molecular Formula	C6H6ClNO
Molar Mass	143.57
Density	1.324±0.06 g/cm3(Predicted)
Melting Point	65.5 °C
Boling Point	279.0±25.0 °C(Predicted)
Flash Point	108.2°C
Vapor Presure	0.0264mmHg at 25°C
Appearance	Crystallization
Maximum wavelength(λmax)	262nm(MeOH)(lit.)
pKa	13.08±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.583
MDL	MFCD06858767

2-CHLORO-4-HYDROXYMETHYLPYRIDINE - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany	3
Hazard Note	Harmful
Hazard Class	IRRITANT

2-CHLORO-4-HYDROXYMETHYLPYRIDINE - Introduction

(2-chloropyridin-4-yl) methanol is an organic compound whose chemical formula is C7H6ClNO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
(2-Chloropyridin-4-yl) methanol is a white crystalline solid with a distinctive odor. It is insoluble in water at normal temperature and pressure, but soluble in organic solvents such as ethanol and dichloromethane. The compound is stable in air, but may have oxidation reaction under light.

Use:
(2-chloropyridin-4-yl) methanol has a wide range of applications in the field of organic synthesis. It can be used as an intermediate in drug synthesis and play an important role in the synthesis of drugs, pesticides and veterinary drugs. In addition, (2-chloropyridin-4-yl) methanol can also be used in the synthesis of dyes and coatings.

Preparation Method:
(2-chloropyridin-4-yl) methanol is generally prepared by the reaction of 2-chloropyridine and methanol. Specifically, 2-chloropyridine and methanol are added to a reactor, and after heating and stirring the reaction mixture for a certain period of time, the product is obtained by cooling crystallization.

Safety Information:
(2-chloropyridin-4-yl) methanol is an organic compound and is a flammable substance. Contact with high temperature, open flame and oxidant should be avoided during operation. Appropriate protective gloves and eye protection should be worn during use to ensure a well-ventilated operating environment. If the compound is accidentally exposed or inhaled, rinse immediately with plenty of water and seek medical help. During storage, the compound should be stored in a cool, dry, well-ventilated place, away from fire and away from light.

Last Update：2024-04-09 20:52:54