2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE

2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE - Names and Identifiers

Name	N-[(6-Chloropyridin-3-yl)methyl]methylamine
Synonyms	2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE 6-chloro-N-methyl-3-pyridinemethanamine N-[(6-Chloropyridin-3-yl)methyl]methylamine N-[(6-CHLOROPYRIDIN-3-YL)METHYL]-N-METHYLAMINE 1-(6-chloro-3-pyridinyl)-N-methylmethanamine 1.4 HCl [(6-chloropyridin-3-yl)methyl]methylamine dihydrochloride 1-(6-Chloro-3-pyridinyl)-N-methylmethanamine dihydrochloride 1-(6-Chloropyridin-3-yl)-N-MethylMethanaMine dihydrochloride
CAS	120739-62-0

2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE - Physico-chemical Properties

Molecular Formula	C7H9ClN2
Molar Mass	156.61
Density	1.149±0.06 g/cm3(Predicted)
Boling Point	236.9±25.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Sparingly)
Appearance	Solid
Color	Clear Pale Yellow Oil to Off-White to Pale Yellow Low-Melting
pKa	8.08±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Hazard Class	IRRITANT

2-CHLORO-5-(METHYLAMINOMETHYL)PYRIDINE - Introduction

N-[(6-Chloropyridin-3-yl)methyl]methylamine is an organic compound with the chemical formula C7H9ClN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: N-[(6-Chloropyridin-3-yl)methyl]methylamine is a colorless to pale yellow oily liquid.
-Solubility: It has low solubility in water, but it can be dissolved in some organic solvents, such as ethanol, ether and ketone.
-Melting point: About -20 ℃.
-Boiling point: about 165-167 ℃.

Use:
- N-[(6-chloropyrin-3-yl) methyl]methylamine can be used as an intermediate in organic synthesis.
-It is often used in the preparation of drugs, such as anti-tumor drugs.

Preparation Method:
The preparation of N-[(6-Chloropyridin-3-yl)methyl]methylamine usually involves the following steps:
1. 6-chloropyridine was reacted with hydrogen in an ammonia atmosphere to obtain 6-chloropyridin-3-ylmethylamine.
2. 6-chloropyridin-3-ylmethylamine is reacted with a methylating agent, such as methyl magnesium iodide or methyl iodide, to obtain N-[(6-Chloropyridin-3-yl)methyl]methylamine.

Safety Information:
- N-[(6-chloropyrin-3-yl) methyl] methyamine shall comply with the safety procedures of the regular laboratory during use and storage.
-It is an organic compound that may cause irritation and damage to the human body. During the operation, contact with skin, eyes and respiratory tract should be avoided. Use personal protective equipment such as protective gloves, goggles and respirators.

Please note that the use and handling of chemicals need to be cautious and carried out under suitable conditions. It is recommended to use this compound in a professional laboratory environment and follow relevant safety guidelines and regulations.

Last Update：2024-04-09 15:18:07