2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE

2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE - Names and Identifiers

Name	2-chloro-5-fluoro-pyridin-3-ol
Synonyms	2-CHLORO-5-FLUORO-PYRIDIN-3-OL 2-chloro-5-fluoro-pyridin-3-ol 3-Pyridinol, 2-chloro-5-fluoro- 2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE 2-Chloro-5-fluoro-3-hydroxypyridine
CAS	884494-35-3
InChI	InChI=1/C5H3ClFNO/c6-5-4(9)1-3(7)2-8-5/h1-2,9H

2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE - Physico-chemical Properties

Molecular Formula	C5H3ClFNO
Molar Mass	147.53
Density	1.517±0.06 g/cm3(Predicted)
Boling Point	302.0±37.0 °C(Predicted)
Flash Point	100℃
Vapor Presure	0.000567mmHg at 25°C
pKa	3.55±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.552

2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
Hazard Class	IRRITANT

2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE - Introduction

It is an organic compound with the chemical formula C5H3ClFNO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: It is a colorless to light yellow solid.
-Solubility: It has poor solubility in water, but it can be dissolved in organic solvents such as ethanol and dimethyl sulfoxide.
-Storage stability: Store in a dry, cool place, avoid direct sunlight.

Use:
-is often used as an intermediate in organic synthesis. It can be used in the preparation of pesticides, pharmaceuticals and other organic compounds.
-The compound can also be used as a catalyst or ligand.

Preparation Method: The preparation of
-fluoropyridine can usually be obtained by reacting 2-chloro-3-nitro-5-fluoropyridine with a ferrous reducing agent.

Safety Information:
-The safety is high, but it is still recommended to take appropriate safety measures during use, such as wearing protective gloves and glasses.
-Avoid inhalation or contact with the compound, especially to avoid long-term exposure.
-If inhaled or touched, wash immediately and seek medical advice.
-When using or disposing of this compound, please follow safe operating procedures and handle it in accordance with local regulations.

Last Update：2024-04-09 15:18:00