2-CHLORO-5-FLUORO-4-IODOPYRIDINE

2-CHLORO-5-FLUORO-4-IODOPYRIDINE - Names and Identifiers

Name	2-chloro-5-fluoro-4-iodopyridine
Synonyms	Methyl 7-bromopicolinate 2-CHLORO-5-FLUORO-4-IODOPYRIDINE 2-chloro-5-fluoro-4-iodopyridine pyridine, 2-chloro-5-fluoro-4-iodo- Pyridine, 2-chloro-5-fluoro-4-iodo-
CAS	884494-49-9
InChI	InChI=1/C5H2ClFIN/c6-5-1-4(8)3(7)2-9-5/h1-2H
InChIKey	CRLPRXQOSARJCF-UHFFFAOYSA-N

2-CHLORO-5-FLUORO-4-IODOPYRIDINE - Physico-chemical Properties

Molecular Formula	C5H2ClFIN
Molar Mass	257.43
Density	2.129
Boling Point	242℃
Flash Point	100℃
Vapor Presure	0.053mmHg at 25°C
pKa	-2.37±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.614
MDL	MFCD03095306

2-CHLORO-5-FLUORO-4-IODOPYRIDINE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

2-CHLORO-5-FLUORO-4-IODOPYRIDINE - Introduction

It is an organic compound with the chemical formula C5H2ClFIN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow crystal or powder
-Melting point: 90-94°C
-Boiling Point: 220-222°C
-Density: 1.976g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and chloroform

Use:
is an important intermediate compound, which can be used to synthesize pyridine derivatives and drugs. It has potential anti-tumor and antibacterial activities in the field of medicine, so it has certain application potential in drug research and development.

Preparation Method:
The synthesis of fluorophase can be achieved by reacting 4-iodopyridine with chloroform and introducing a fluorinating reagent under alkaline conditions. Specific synthetic steps include iodination reaction, chlorination reaction and fluorination reaction, etc.

Safety Information:
-shall be treated as a hazardous chemical and shall be handled with appropriate safety measures.
-Avoid inhalation, skin contact and eye contact during handling, use and storage, and always wear appropriate personal protective equipment.
-If you are accidentally exposed or taken by mistake, you should seek medical advice immediately and bring the relevant chemical safety data sheet for your doctor's reference.

Please note that the above information is for reference only and is not exhaustive. In practice, always refer to specific chemical safety data sheets and relevant laboratory practices.

Last Update：2024-04-09 15:18:00