2-CHLOROISONICOTINALDEHYDE

2-CHLOROISONICOTINALDEHYDE - Names and Identifiers

Name	2-Chloroisonicotinaldehyde
Synonyms	2-Chloro-4-Formylpyridine 2-CHLORO-4-FORMYLPYRIDINE CHLORO-2-FORMYL-3-PYRIDINE 2-CHLOROISONICOTINALDEHYDE 2-Chloroisonicotinaldehyde 2-CHLOROPYRIDINE-4-CARBALDEHYDE 2-CHLORO-PYRIDIN-3-CARBALDEHYDE 2-Chloropyridine-4-Carbaldehyde 2-Chloropyridine-4-Carboxaldehyde 2-CHLOROPYRIDINE-3-CARBOXALDEHYDE 2-CHLOROPYRIDINE-4-CARBOXALDEHYDE 2-Chloro-4-Pyridinecarboxaldehyde
CAS	101066-61-9
InChI	InChI=1/C6H4ClNO/c7-6-3-5(4-9)1-2-8-6/h1-4H

2-CHLOROISONICOTINALDEHYDE - Physico-chemical Properties

Molecular Formula	C6H4ClNO
Molar Mass	141.56
Density	1.332±0.06 g/cm3(Predicted)
Melting Point	46-50 °C
Boling Point	243.4±20.0 °C(Predicted)
Flash Point	>230°C
Vapor Presure	0.0321mmHg at 25°C
Appearance	Solid
Color	White to Almost white
BRN	7986625
pKa	-1.23±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.592
MDL	MFCD06651557
Physical and Chemical Properties	Sensitivity: Air Sensitive WGK Germany:3

2-CHLOROISONICOTINALDEHYDE - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R42/43 - May cause sensitization by inhalation and skin contact.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S23 - Do not breathe vapour.
WGK Germany	3
Hazard Note	Harmful
Hazard Class	IRRITANT

2-CHLOROISONICOTINALDEHYDE - Introduction

2-Chloropyridine-4-carbaldehyde is an organic compound with the chemical formula C6H4ClNO. The following is a description of its nature, use, preparation and safety information:

Properties: 2-Chloropyridine-4-formaldehyde is a colorless to light yellow liquid with a special odor. It has good solubility at room temperature, soluble in water and most organic solvents. It is an organic aldehyde compound with certain reactivity.

use: 2-chloropyridine -4-formaldehyde in organic synthesis has a wide range of applications. It is a known important intermediate and functional reagent, can be used in the preparation of various organic compounds, such as pyridine derivatives, amino acids, etc. In addition, it can also be used for the synthesis of dyes, glyphosate and other chemicals.

Preparation Method: A common preparation method is obtained by reacting pyridine with 2-chloropropionaldehyde. The reaction is generally carried out at room temperature under alkaline or acidic conditions. In the specific operation, pyridine and 2-chloropropionaldehyde can be mixed according to a certain material ratio, and reacted for a certain time under suitable conditions, and then the target product can be obtained through process steps such as extraction and crystallization.

Safety information: 2-chloropyridine-4-formaldehyde requires attention to safety during use and storage. It is an organic substance, which is irritating and corrosive, and may cause irritation to the skin, eyes and respiratory tract. Therefore, appropriate personal protective equipment such as gloves, goggles and protective masks should be worn during operation. At the same time, it is also very important to maintain a well-ventilated working environment. During storage, it should be kept in a sealed container to avoid contact with oxygen, fire, etc., to avoid fire and explosion. In the event of an accident, appropriate first aid measures should be taken and medical attention should be sought immediately. Before using 2-chloropyridine-4-carbaldehyde, the safety manual and related information should be understood in detail.

Last Update：2024-04-10 22:29:15