2-CHLOROMETHYL-4-BENZYLMORPHOLINE - Names and Identifiers
2-CHLOROMETHYL-4-BENZYLMORPHOLINE - Physico-chemical Properties
Molecular Formula | C12H16ClNO
|
Molar Mass | 225.71 |
Density | 1.132±0.06 g/cm3(Predicted) |
Melting Point | 46 °C |
Boling Point | 120-122°C 1mm |
Flash Point | 144.1°C |
Vapor Presure | 0.00046mmHg at 25°C |
pKa | 6.09±0.10(Predicted) |
Storage Condition | 2-8°C |
2-CHLOROMETHYL-4-BENZYLMORPHOLINE - Risk and Safety
Hazard Symbols | C - Corrosive
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
R36 - Irritating to the eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
Hazard Class | IRRITANT |
2-CHLOROMETHYL-4-BENZYLMORPHOLINE - Introduction
4-benzyl-2-(chloromethyl)morpholine is an organic compound whose chemical formula is C15H18ClNO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Melting point:-7°C
-Boiling Point: 262-264°C
-Solubility: Soluble in alcohol and ether
Use:
4-benzyl-2-(chloromethyl)morpholine can be used as an intermediate and has certain applications in pharmaceutical synthesis and organic synthesis. It can be used in the preparation of medicines for the treatment of colds and flu. In addition, it can also be used as a catalyst in organic synthesis reactions.
Preparation Method:
The preparation of 4-benzyl-2-(chloromethyl)morpholine can be carried out by the following steps:
1.2-chloromethylmorphorphine reacts with benzyl bromide under alkaline conditions.
2. Gently heat the reaction mixture to cause transesterification.
3. The reaction mixture was further worked up to purify the resulting product.
Safety Information:
4-benzyl-2-(chloromethyl)morpholine in the use and operation should pay attention to the following safety matters:
-It is an irritating compound that may irritate the eyes and skin. Wear appropriate protective gloves and eye protection during operation.
-During storage and handling, avoid reacting with oxidants and strong acids to avoid the generation of harmful gases.
-The toxicity and carcinogenicity data of this compound are limited, so caution should be used and handled, and relevant safety procedures should be followed.
Last Update:2024-04-09 20:52:54