2-Chloro-3,5-difluoroaniline
2-Chloro-3,5-difluoroaniline
CAS: 36556-60-2
Molecular Formula: C6H4ClF2N
2-Chloro-3,5-difluoroaniline - Names and Identifiers
2-Chloro-3,5-difluoroaniline - Physico-chemical Properties
| Molecular Formula | C6H4ClF2N |
| Molar Mass | 163.55 |
| Density | 1.434 |
| Melting Point | 26-28 |
| Boling Point | 208.3±35.0 °C(Predicted) |
| Flash Point | 92 |
| pKa | 0.62±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.53 |
2-Chloro-3,5-difluoroaniline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Harmful/Irritant |
2-Chloro-3,5-difluoroaniline - Introduction
2-Chloro-3,5-difluoroaniline is an organic compound with the formula C6H4ClF2N. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Chloro-3,5-difluoroaniline is a white to light yellow crystal or crystalline powder.
-Melting point: Its melting point range is about 98-100 degrees Celsius.
-Solubility: 2-Chloro-3,5-difluoroaniline is soluble in commonly used organic solvents, such as alcohols, ethers and ketones.
-Stability: It is relatively stable at room temperature and can be stored for a long time under dark conditions.
Use:
- 2-Chloro-3,5-difluoroaniline is commonly used as an intermediate in organic synthesis.
-It can be used to synthesize pesticides, dyes, medicines and other organic compounds.
-Due to its specific chemical properties, it can also be used as a dye intermediate.
-It also has some applications in the pharmaceutical field, such as as a synthetic precursor for compounds.
Preparation Method:
2-Chloro-3,5-difluoroaniline is usually prepared by the following two methods:
1. Obtain by fluorination and chlorination on the benzene ring.
2. by the reduction reaction of 2-chlorine -3,5-difluoronitrobenzene.
Safety Information:
- 2-Chloro-3,5-difluoroaniline is a toxic compound and should be handled with care. Avoid contact with skin and eyes during use.
-During operation, good ventilation should be provided to reduce the vapor concentration.
-In storage and handling, should follow the appropriate safety procedures, such as wearing protective gloves and safety glasses.
-If contact or inhalation occurs, immediately flush the affected area with clean water and seek medical help.
Nature:
-Appearance: 2-Chloro-3,5-difluoroaniline is a white to light yellow crystal or crystalline powder.
-Melting point: Its melting point range is about 98-100 degrees Celsius.
-Solubility: 2-Chloro-3,5-difluoroaniline is soluble in commonly used organic solvents, such as alcohols, ethers and ketones.
-Stability: It is relatively stable at room temperature and can be stored for a long time under dark conditions.
Use:
- 2-Chloro-3,5-difluoroaniline is commonly used as an intermediate in organic synthesis.
-It can be used to synthesize pesticides, dyes, medicines and other organic compounds.
-Due to its specific chemical properties, it can also be used as a dye intermediate.
-It also has some applications in the pharmaceutical field, such as as a synthetic precursor for compounds.
Preparation Method:
2-Chloro-3,5-difluoroaniline is usually prepared by the following two methods:
1. Obtain by fluorination and chlorination on the benzene ring.
2. by the reduction reaction of 2-chlorine -3,5-difluoronitrobenzene.
Safety Information:
- 2-Chloro-3,5-difluoroaniline is a toxic compound and should be handled with care. Avoid contact with skin and eyes during use.
-During operation, good ventilation should be provided to reduce the vapor concentration.
-In storage and handling, should follow the appropriate safety procedures, such as wearing protective gloves and safety glasses.
-If contact or inhalation occurs, immediately flush the affected area with clean water and seek medical help.
Last Update：2024-04-09 21:04:16
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CAS: 36556-60-2
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View History
2-Chloro-3,5-difluoroaniline
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16903-61-0
alpha-Maleinimido-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 3.000 Dalton)
Epoxide-PEG-Epoxide
Polydimethylhydrosiloxan
112-71-0
2,2-二氟-2-(3-(三氟甲基)苯基)乙-1-醇
1204-60-0
152922-71-9
2894-67-9