2-Chloro-4-methyl-5-iodopyridine

2-Chloro-4-methyl-5-iodopyridine - Names and Identifiers

Name	2-chloro-5-iodo-4-methylpyridine
Synonyms	2-Chloro-4-Methyl-5-Iodopyridine 2-Chloro-4-methyl-5-iodopyridine 2-Chloro-5-iodo-4-methylpyridine 2-chloro-5-iodo-4-methylpyridine 2-Chloro-5-iodo-4-methyl-pyridine Pyridine, 2-chloro-5-iodo-4-methyl- 2-Fluoro-5-iodo-6-picoline 6-Fluoro-3-iodo-2-picoline
CAS	550347-54-1
InChI	InChI=1/C6H5ClIN/c1-4-2-6(7)9-3-5(4)8/h2-3H,1H3

2-Chloro-4-methyl-5-iodopyridine - Physico-chemical Properties

Molecular Formula	C6H5ClIN
Molar Mass	253.47
Density	1.906±0.06 g/cm3(Predicted)
Boling Point	279.4±35.0 °C(Predicted)
pKa	-1.20±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.624

2-Chloro-4-methyl-5-iodopyridine - Introduction

It is an organic compound with the chemical formula of C6H5ClIN. There is a chlorine atom, an iodine atom and a methyl group substituted on the pyridine ring.

Properties of the compound:
-Appearance: White to yellowish solid
-Density: approx. 2.01g/cm³
-Melting point: about 87-89°C
-Boiling point: about 233-235°C
-solubility: soluble in most organic solvents, such as ethanol, ether, insoluble in water.

Its main uses include:
-Organic synthesis: It is a commonly used chemical intermediate that can be used to synthesize other compounds, such as heterocyclic compounds, drug molecules, etc.
-Pesticide research and development: This compound is also used in the research and development and production of pesticides.

The preparation method is generally carried out by the following steps:
1. pyridine and formic acid react to generate 2-methyl pyridine.
2.2-methyl pyridine is reacted with sodium hydroxide and iodine to obtain 2-methyl -5-iodine pyridine.
3. Finally, 2-methyl -5-iodopyridine is reacted with cuprous chloride to obtain chromium.

About safety information:
-is an organic compound that requires safe handling, avoiding contact with skin, breathing or swallowing.
-Wear appropriate protective equipment such as gloves, glasses and protective clothing during operation.
-When storing, keep it in a sealed container and keep it away from fire sources or flammable substances.
-If exposed to the substance, rinse immediately with plenty of water and seek medical help.

It should be emphasized that this information is for reference only. Please follow the relevant safe operation procedures and usage methods of chemicals in actual operation.

Last Update：2024-04-09 21:00:56