2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxabaorolan-2-yl)pyridine - Names and Identifiers
Name | 2-Chloro-5-pyridylboronic acid pinacol ester
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Synonyms | AKOS BRN-0198 RARECHEM AK ML 0445 2-Chloropyridine-5-boronicacidpinacolester 2-CHLORO-5-PYRIDYLBORONIC ACID PINACOL ESTER 2-Chloro-5-pyridylboronic acid pinacol ester 6-CHLOROPYRIDINE-3-BORONIC ACID PINACOL ESTER 6-Chloropyridine-3-boronic acid pinacol ester 2-CHLORO-5-PYRIDINEBORONIC ACID PINACOL ESTER 6-CHLOROPYRIDIN-3-YLBORONIC ACID PINACOL ESTER 2-CHLOROPYRIDINE-5-BORONIC ACID, PINACOL ESTER 2-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxabaorolan-2-yl)pyridine
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CAS | 444120-94-9
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InChI | InChI=1/C11H15BClNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-9(13)14-7-8/h5-7H,1-4H3 |
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxabaorolan-2-yl)pyridine - Physico-chemical Properties
Molecular Formula | C11H15BClNO2
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Molar Mass | 239.51 |
Density | 1.14±0.1 g/cm3(Predicted) |
Melting Point | 86-90°C |
Boling Point | 328.3±27.0 °C(Predicted) |
Flash Point | 152.4°C |
Vapor Presure | 0.000364mmHg at 25°C |
pKa | 0.17±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.505 |
MDL | MFCD03412793 |
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxabaorolan-2-yl)pyridine - Risk and Safety
Risk Codes | R36 - Irritating to the eyes
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
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Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxabaorolan-2-yl)pyridine - Introduction
2-Chloro-5-pyridylboronic acid pinacol ester is an organic compound with the chemical formula C11H15BClNO2. It is a solid, usually in the form of white crystals.
The compound is widely used in organic synthesis. It is an important reagent for the esterification of alcohols and can be used for the synthesis of various boron-containing compounds. In addition, it can also be used as an organic nucleophile to participate in various reactions such as phenyl substitution reactions and condensation reactions.
the preparation of 2-Chloro-5-pyridylboronic acid pinacol ester is usually obtained by reacting boric acid with 2-chloro-5-pyridylmethanol. The reaction conditions are generally at room temperature, and dimethyl sulfoxide (DMSO) is usually used as a solvent, and stirring is required during the reaction.
Regarding safety information, 2-Chloro-5-pyridylboronic acid pinacol ester is generally safe in routine operation, but it is still necessary to pay attention to some routine laboratory safety. During use, contact with skin, eyes and respiratory tract should be avoided. At the same time, maintain good ventilation and wear appropriate personal protective equipment, such as laboratory gloves and goggles. In the event of accidental exposure to the compound, rinse immediately with plenty of water and seek medical attention if necessary.
Last Update:2024-04-10 22:29:15