2-Chloro-5-iodopyridin-3-aMine

2-Chloro-5-iodopyridin-3-aMine - Names and Identifiers

Name	2-chloro-5-iodopyridin-3-amine
Synonyms	2-chloro-5-iodopyridin-3-amine 2-Chloro-5-iodopyridin-3-aMine 2-chloro-5-iodo-3-pyridinamine 3-AMINO-2-CHLORO-5-IODOPYRIDINE 2-Chloro-3-amino--5-iodopyridine 3-PyridinaMine, 2-chloro-5-iodo- 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE
CAS	426463-09-4
InChI	InChI=1/C5H4ClIN2/c6-5-4(8)1-3(7)2-9-5/h1-2H,8H2

2-Chloro-5-iodopyridin-3-aMine - Physico-chemical Properties

Molecular Formula	C5H4ClIN2
Molar Mass	254.46
Density	2.139±0.06 g/cm3(Predicted)
Melting Point	128-133°C
Boling Point	352.5±42.0 °C(Predicted)
Flash Point	167°C
Vapor Presure	3.81E-05mmHg at 25°C
pKa	0.27±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.707

2-Chloro-5-iodopyridin-3-aMine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

2-Chloro-5-iodopyridin-3-aMine - Introduction

It is an organic compound with the chemical formula C5H4ClIN2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
is a solid compound with a white or off-white crystalline appearance. It is almost insoluble in water at room temperature, but easily soluble in common organic solvents such as ethanol, acetone and dimethylthiourea. It has a melting point and a boiling point of about 140-141°C and about 290-291°C, respectively.

Use:
It is an important organic synthesis intermediate that can be used to synthesize other compounds. It is commonly used in the pharmaceutical field to synthesize biologically active compounds, such as drugs and pesticides. In addition, it can also be used as a chemical reagent to participate in organic synthesis reactions.

Preparation Method:
It can be synthesized by the following methods: first, 2-chloro-5-iodopyridine and ammonia are reacted to generate the corresponding 3-amino-2-iodo-5-iodopyridine compound; and then through reduction or other chemical reactions, Replace the iodine atom with the chlorine atom to get the pyridine.

Safety Information:
General laboratory safety procedures need to be followed for the safety information. It may be irritating to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as chemical goggles, protective gloves and breathing masks during use. In addition, avoid inhaling its dust or contact with skin. When handling the compound, ensure that the operation is carried out in a well-ventilated environment. Whether you store or dispose of waste, you must follow the appropriate regulations and procedures.

Last Update：2024-04-09 21:54:55