2-Chloro-5-methylthiophene
2-Chloro-5-methylthiophene
CAS: 17249-82-0
Molecular Formula: C5H5ClS
2-Chloro-5-methylthiophene - Names and Identifiers
| Name | 2-Chloro-5-methylthiophene |
| Synonyms | 2-CHLORO-5-METHYLTHIOPHENE 2-Chloro-5-methylthiophene Thiophene, 2-chloro-5-methyl- |
| CAS | 17249-82-0 |
| InChI | InChI=1/C5H5ClS/c1-4-2-3-5(6)7-4/h2-3H,1H3 |
2-Chloro-5-methylthiophene - Physico-chemical Properties
| Molecular Formula | C5H5ClS |
| Molar Mass | 132.61 |
| Density | 1.21 |
| Boling Point | 155-156°C |
| Flash Point | 155-156°C |
| Water Solubility | Not miscible or difficult to mix with water. |
| Vapor Presure | 4.6mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Light yellow to Light orange |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.5356 |
2-Chloro-5-methylthiophene - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 1993 3/PG III |
| HS Code | 29349990 |
| Hazard Class | 3 |
| Packing Group | III |
2-Chloro-5-methylthiophene - Introduction
2-Chloro-5-methylthiophene, also known as 2-chloro-5-toluenethiol, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
2-Chloro-5-methylthiophene is a colorless liquid with a strong sulfur odor. At room temperature, the density is large, the boiling point is 84-85 degrees Celsius, and the molecular formula is C7H7ClS.
Use:
2-Chloro-5-methylthiophene is commonly used in organic synthesis reactions as a protecting group remover for alcohols, ethers, aldehydes and other compounds, and can realize the conversion from thiol to alcohol or ether. In addition, it can also be used as a solvent in organic synthesis.
Method:
2-Chloro-5-methylthiophene can be prepared by reacting toluene with phosphorus chloride. The specific reaction condition is that phosphorus chloride is added in a solvent and stirred, then toluene is slowly added dropwise, and after the reaction is complete, the organic phase is separated after washing with water to obtain the target product.
Safety Information:
2-Chloro-5-methylthiophene is irritating and corrosive, and contact with skin and eyes may cause irritation and burns. Appropriate personal protective equipment such as gloves, goggles and protective clothing should be worn during operation. At the same time, make sure to operate in a well-ventilated place to avoid inhaling gas vapor. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. In addition, the compound is also a flammable liquid, should avoid contact with open flame and high temperature.
Nature:
2-Chloro-5-methylthiophene is a colorless liquid with a strong sulfur odor. At room temperature, the density is large, the boiling point is 84-85 degrees Celsius, and the molecular formula is C7H7ClS.
Use:
2-Chloro-5-methylthiophene is commonly used in organic synthesis reactions as a protecting group remover for alcohols, ethers, aldehydes and other compounds, and can realize the conversion from thiol to alcohol or ether. In addition, it can also be used as a solvent in organic synthesis.
Method:
2-Chloro-5-methylthiophene can be prepared by reacting toluene with phosphorus chloride. The specific reaction condition is that phosphorus chloride is added in a solvent and stirred, then toluene is slowly added dropwise, and after the reaction is complete, the organic phase is separated after washing with water to obtain the target product.
Safety Information:
2-Chloro-5-methylthiophene is irritating and corrosive, and contact with skin and eyes may cause irritation and burns. Appropriate personal protective equipment such as gloves, goggles and protective clothing should be worn during operation. At the same time, make sure to operate in a well-ventilated place to avoid inhaling gas vapor. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. In addition, the compound is also a flammable liquid, should avoid contact with open flame and high temperature.
Last Update：2024-04-10 22:29:15
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Product Name: 2-Chloro-5-methylthiophene Visit Supplier Webpage Request for quotationCAS: 17249-82-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Chloro-5-methylthiophene Visit Supplier Webpage Request for quotationCAS: 17249-82-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
2-Chloro-5-methylthiophene
141943-04-6
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4-(5-methoxypyridin-2-yl)phenol
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3,5-Bis(trifluoromethyl)benzonitrile