2-Chloro-5-nitrophenylboronicacid
(2-chloro-5-nitro-phenyl)boronic acid
CAS: 867333-29-7
Molecular Formula: C6H5BClNO4
2-Chloro-5-nitrophenylboronicacid - Names and Identifiers
2-Chloro-5-nitrophenylboronicacid - Physico-chemical Properties
| Molecular Formula | C6H5BClNO4 |
| Molar Mass | 201.37 |
| Density | 1.54±0.1 g/cm3(Predicted) |
| Melting Point | 236-238 |
| Boling Point | 392.9±52.0 °C(Predicted) |
| Flash Point | 191.4°C |
| Vapor Presure | 7.08E-07mmHg at 25°C |
| pKa | 6.63±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.592 |
2-Chloro-5-nitrophenylboronicacid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
2-Chloro-5-nitrophenylboronicacid - Introduction
(2-chroo-5-nyro-phenyl) boronic acid is an organic compound whose chemical formula is C6H5BClNO4. The following is a description of its nature, use, preparation and safety information:
Nature:
(2-chloro-5-nitro-phenyl)boronic acid is a white to light yellow crystal, soluble in some organic solvents such as dimethyl sulfoxide and ethanol, insoluble in water. It is a stable compound and does not easily decompose at room temperature.
Use:
(2-chroo-5-nyro-phenyl) boronic acid is an important organic synthesis reagent. It is commonly used in Suzuki coupling reactions in organic synthesis for the construction of carbon-carbon bonds of aromatic compounds. In addition, it can also act as a ligand for metal catalysts.
Preparation Method:
(2-chloro-5-nitro-phenyl) The preparation method of boronic acid usually uses boric acid and the corresponding nitroaromatic compound to react. The specific method is to first react boric acid and cuprous chloride in an aqueous solution to obtain 2-chlorophenylboronic acid. 2-Chlorophenylboronic acid was then reacted with silver nitrooxalate in ammonia solution to form (2-chloro-5-nitro-phenyl)boronic acid.
Safety Information:
It is understood that (2-chloro-5-nitro-phenyl)boronic acid generally does not cause serious safety risks under normal use conditions. However, as a chemical substance, it still needs to follow some safe operating procedures. During operation, wear appropriate protective gloves and glasses to avoid contact with skin and eyes. In addition, care should be taken to avoid inhaling the gas of its dust or solution. If contact with skin or eyes, should immediately rinse with plenty of water, and timely medical treatment. In addition, the compound should be stored in a dry, cool place, away from fire and oxidizing agents.
Nature:
(2-chloro-5-nitro-phenyl)boronic acid is a white to light yellow crystal, soluble in some organic solvents such as dimethyl sulfoxide and ethanol, insoluble in water. It is a stable compound and does not easily decompose at room temperature.
Use:
(2-chroo-5-nyro-phenyl) boronic acid is an important organic synthesis reagent. It is commonly used in Suzuki coupling reactions in organic synthesis for the construction of carbon-carbon bonds of aromatic compounds. In addition, it can also act as a ligand for metal catalysts.
Preparation Method:
(2-chloro-5-nitro-phenyl) The preparation method of boronic acid usually uses boric acid and the corresponding nitroaromatic compound to react. The specific method is to first react boric acid and cuprous chloride in an aqueous solution to obtain 2-chlorophenylboronic acid. 2-Chlorophenylboronic acid was then reacted with silver nitrooxalate in ammonia solution to form (2-chloro-5-nitro-phenyl)boronic acid.
Safety Information:
It is understood that (2-chloro-5-nitro-phenyl)boronic acid generally does not cause serious safety risks under normal use conditions. However, as a chemical substance, it still needs to follow some safe operating procedures. During operation, wear appropriate protective gloves and glasses to avoid contact with skin and eyes. In addition, care should be taken to avoid inhaling the gas of its dust or solution. If contact with skin or eyes, should immediately rinse with plenty of water, and timely medical treatment. In addition, the compound should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
