2-Chloro-6-(Hydroxymethyl)Pyridine
(6-Chloro-2-pyridinyl)methanol
CAS: 33674-97-4
Molecular Formula: C6H6ClNO
2-Chloro-6-(Hydroxymethyl)Pyridine - Names and Identifiers
| Name | (6-Chloro-2-pyridinyl)methanol |
| Synonyms | CHEMPACIFIC 38159 6-Chloro-2-pyridinemethanol 2-Chloropyridine-6-Methanol 2-Pyridinemethanol, 6-chloro- (6-Chloro-2-pyridinyl)methanol (6-Chloropyridin-2-yl)methanol (6-CHLORO-PYRIDIN-2-YL)-METHANOL 2-Chloro-6-(Hydroxymethyl)Pyridine |
| CAS | 33674-97-4 |
| EINECS | 807-010-1 |
| InChI | InChI=1/C6H6ClNO/c7-6-3-1-2-5(4-9)8-6/h1-3,9H,4H2 |
2-Chloro-6-(Hydroxymethyl)Pyridine - Physico-chemical Properties
| Molecular Formula | C6H6ClNO |
| Molar Mass | 143.57 |
| Density | 1.324±0.06 g/cm3(Predicted) |
| Boling Point | 251.8±25.0 °C(Predicted) |
| Flash Point | 106.1°C |
| Vapor Presure | 0.0105mmHg at 25°C |
| pKa | 13.12±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.572 |
2-Chloro-6-(Hydroxymethyl)Pyridine - Risk and Safety
| Hazard Class | IRRITANT |
2-Chloro-6-(Hydroxymethyl)Pyridine - Introduction
(6-Chloro-2-pyridinyl)methanol is an organic compound whose chemical formula is C6H6ClNO. It has a colorless to yellow crystalline solid form.
Regarding the properties,(6-Chloro-2-pyridinyl)methanol is hardly soluble in water at room temperature, but it can be soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. Its melting point is about 70-75 degrees Celsius.
This compound is often used as an intermediate in organic synthesis, especially in the field of medicine. It can be used to synthesize compounds containing pyridine structures, which play an important role in drug research and development. In addition, it is also used as an ingredient of insecticides or pesticides to control the growth and reproduction of some pests.
Regarding the preparation method, a common synthesis method is to reduce 2-cyano-6-chloropyridine to obtain (6-Chloro-2-pyridinyl)methanol. Sulfite, hydrogen or hydride can be selected as the reducing agent for the reaction, and the reaction conditions can be adjusted according to the actual situation.
Regarding safety information,(6-Chloro-2-pyridinyl)methanol should be stored in a dry and ventilated place, away from fire and high temperature. It is necessary to pay attention to protective measures, such as wearing gloves, goggles and protective clothing. In addition, it needs to be kept away from children and animals, avoiding direct contact with the skin and inhaling its dust or gas. In case of careless contact, rinse with plenty of water in time and seek medical treatment.
Regarding the properties,(6-Chloro-2-pyridinyl)methanol is hardly soluble in water at room temperature, but it can be soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. Its melting point is about 70-75 degrees Celsius.
This compound is often used as an intermediate in organic synthesis, especially in the field of medicine. It can be used to synthesize compounds containing pyridine structures, which play an important role in drug research and development. In addition, it is also used as an ingredient of insecticides or pesticides to control the growth and reproduction of some pests.
Regarding the preparation method, a common synthesis method is to reduce 2-cyano-6-chloropyridine to obtain (6-Chloro-2-pyridinyl)methanol. Sulfite, hydrogen or hydride can be selected as the reducing agent for the reaction, and the reaction conditions can be adjusted according to the actual situation.
Regarding safety information,(6-Chloro-2-pyridinyl)methanol should be stored in a dry and ventilated place, away from fire and high temperature. It is necessary to pay attention to protective measures, such as wearing gloves, goggles and protective clothing. In addition, it needs to be kept away from children and animals, avoiding direct contact with the skin and inhaling its dust or gas. In case of careless contact, rinse with plenty of water in time and seek medical treatment.
Last Update：2024-04-09 21:54:55
