2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide
CAS: 112777-30-7
Molecular Formula: C7H7ClN2O2
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide - Names and Identifiers
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide - Physico-chemical Properties
| Molecular Formula | C7H7ClN2O2 |
| Molar Mass | 186.6 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Boling Point | 520.7±50.0 °C(Predicted) |
| pKa | 10.07±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD12922757 |
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide - Introduction
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide, also known as 2-chloro-N-(2-hydroxypyridin-3-yl)acetamide, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide is a white crystalline solid.
-Solubility: Soluble in some organic solvents, such as chloroform and dichloromethane.
-Melting point: Its melting point is about 160-163 degrees Celsius.
-Chemical structure: The compound is formed by connecting an acetamide group with a chlorine-containing benzene ring and a hydroxyl-containing pyridine ring.
Use:
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide has the following application areas:
-Chemical synthesis: As an organic intermediate, it can be used to synthesize other organic compounds, such as drugs, pesticides and coatings.
-Antibacterial activity: The compound has certain antibacterial activity and can be used as a starting compound for the study of new antibacterial agents and antibiotics.
Preparation Method:
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide can be prepared as follows:
-First, under normal alkaline conditions, 2-hydroxypyridine is condensed with chloroacetic acid to obtain 2-chloro-N-(2-hydroxypyridin-3-yl) acetamide.
-Subsequently, it condenses with another molecule of 2-hydroxypyridine under acidic conditions to form 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide.
Safety Information:
There is less safety information about 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide, so you should be cautious when using it. As an organic compound, the basic safety requirements for the use of organic solvents and handling chemicals should generally be followed. When using 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide, wear appropriate protective equipment such as lab gloves and goggles to prevent contact with skin and eyes. In addition, it should be operated under well-ventilated laboratory conditions. For specific safety information and risk assessments, it is recommended to consult the relevant safety data forms or consult a professional.
Nature:
-Appearance: 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide is a white crystalline solid.
-Solubility: Soluble in some organic solvents, such as chloroform and dichloromethane.
-Melting point: Its melting point is about 160-163 degrees Celsius.
-Chemical structure: The compound is formed by connecting an acetamide group with a chlorine-containing benzene ring and a hydroxyl-containing pyridine ring.
Use:
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide has the following application areas:
-Chemical synthesis: As an organic intermediate, it can be used to synthesize other organic compounds, such as drugs, pesticides and coatings.
-Antibacterial activity: The compound has certain antibacterial activity and can be used as a starting compound for the study of new antibacterial agents and antibiotics.
Preparation Method:
2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide can be prepared as follows:
-First, under normal alkaline conditions, 2-hydroxypyridine is condensed with chloroacetic acid to obtain 2-chloro-N-(2-hydroxypyridin-3-yl) acetamide.
-Subsequently, it condenses with another molecule of 2-hydroxypyridine under acidic conditions to form 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide.
Safety Information:
There is less safety information about 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide, so you should be cautious when using it. As an organic compound, the basic safety requirements for the use of organic solvents and handling chemicals should generally be followed. When using 2-Chloro-N-(2-hydroxypyridin-3-yl)acetamide, wear appropriate protective equipment such as lab gloves and goggles to prevent contact with skin and eyes. In addition, it should be operated under well-ventilated laboratory conditions. For specific safety information and risk assessments, it is recommended to consult the relevant safety data forms or consult a professional.
Last Update：2024-04-09 21:54:55
