2-Chloro-N-benzylacetamide
N-Benzyl-2-chloroacetamide
CAS: 2564-06-9
Molecular Formula: C9H10ClNO
2-Chloro-N-benzylacetamide - Names and Identifiers
| Name | N-Benzyl-2-chloroacetamide |
| Synonyms | AKOS B029210 AKOS BBS-00000751 N-CHLOROACETYLBENZYLAMINE N-Benzyl-2-chloroacetamide 2-Chloro-N-benzylacetamide N-Chloroacetylbenzylamine 2-CHLORO-N-BENZYLACETAMIDE 2-chloro-n-(phenylmethyl)acetamide 2-chloro-n-(phenylmethyl)-acetamid ACETAMIDE, 2-CHLORO-N-(PHENYLMETHYL)- |
| CAS | 2564-06-9 |
| InChI | InChI=1/C9H10ClNO/c10-6-9(12)11-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,12) |
2-Chloro-N-benzylacetamide - Physico-chemical Properties
| Molecular Formula | C9H10ClNO |
| Molar Mass | 183.63 |
| Density | 1.1661 g/cm3 |
| Melting Point | 93-96 °C (lit.) |
| Boling Point | 367.5±35.0 °C(Predicted) |
| Flash Point | 176°C |
| Vapor Presure | 1.36E-05mmHg at 25°C |
| pKa | 14.25±0.46(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.539 |
2-Chloro-N-benzylacetamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| RTECS | AB4546570 |
| Hazard Class | IRRITANT |
2-Chloro-N-benzylacetamide - Introduction
N-Benzyl-2-chloroacetamide is an organic compound with the chemical formula C9H10ClNO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
N-Benzyl-2-chloroacetamide are solids that appear as colorless or light yellow crystals at room temperature. It has a special smell. The compound is soluble in some organic solvents, such as ethanol and ether, but poorly soluble in water.
Use:
N-Benzyl-2-chloroacetamide have a variety of applications. One of the main applications is as an important intermediate in organic synthesis, often used in the synthesis of other organic compounds. In addition, it is also used as an insecticide and an antibacterial agent.
Method:
N-Benzyl-2-chloroacetamide is prepared by reacting 2-chloroacetic acid with benzylamine. First, 2-chloroacetic acid is added to thionyl chloride or methylene chloride, and then an appropriate amount of benzylamine is added. After the reaction is carried out, the target product is obtained by the steps of crystallization, filtrate and drying.
Safety Information:
The N-Benzyl-2-chloroacetamide has moderate stability under general conditions of use. However, this compound is combustible and care should be taken to avoid contact with open flames or high temperature heat sources. In addition, it is also an irritant substance and may cause irritation to the eyes, skin and respiratory tract when contacted. Therefore, it is necessary to wear protective gloves and glasses during operation, and make sure to operate in a well-ventilated place.
Nature:
N-Benzyl-2-chloroacetamide are solids that appear as colorless or light yellow crystals at room temperature. It has a special smell. The compound is soluble in some organic solvents, such as ethanol and ether, but poorly soluble in water.
Use:
N-Benzyl-2-chloroacetamide have a variety of applications. One of the main applications is as an important intermediate in organic synthesis, often used in the synthesis of other organic compounds. In addition, it is also used as an insecticide and an antibacterial agent.
Method:
N-Benzyl-2-chloroacetamide is prepared by reacting 2-chloroacetic acid with benzylamine. First, 2-chloroacetic acid is added to thionyl chloride or methylene chloride, and then an appropriate amount of benzylamine is added. After the reaction is carried out, the target product is obtained by the steps of crystallization, filtrate and drying.
Safety Information:
The N-Benzyl-2-chloroacetamide has moderate stability under general conditions of use. However, this compound is combustible and care should be taken to avoid contact with open flames or high temperature heat sources. In addition, it is also an irritant substance and may cause irritation to the eyes, skin and respiratory tract when contacted. Therefore, it is necessary to wear protective gloves and glasses during operation, and make sure to operate in a well-ventilated place.
Last Update：2024-04-10 22:29:15
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