2-Cyano-3-broMo-5-fluoropyridine - Names and Identifiers
2-Cyano-3-broMo-5-fluoropyridine - Physico-chemical Properties
Molecular Formula | C6H3FN2
|
Molar Mass | 122.1 |
Density | 1.24±0.1 g/cm3(Predicted) |
Melting Point | 51-52℃ |
Boling Point | 223.8±20.0 °C(Predicted) |
Flash Point | 89.132°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.095mmHg at 25°C |
Appearance | Solid |
Color | Off-white |
pKa | -3.88±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.51 |
2-Cyano-3-broMo-5-fluoropyridine - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
|
UN IDs | 3439 |
Hazard Class | 6.1 |
Packing Group | Ⅲ |
2-Cyano-3-broMo-5-fluoropyridine - Introduction
5-Cyano-2-fluoropyridine is an organic compound with the chemical formula C6H3FN2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow liquid
-Melting point:-18°C
-Boiling Point: 130-131°C
-Density: 1.279 g/mL
-Solubility: Soluble in many organic solvents, such as ethanol and dimethylformamide
Use:
- 5-Cyano-2-fluoropyridine is often used as an intermediate in organic synthesis for the synthesis of other organic compounds.
-In the pharmaceutical industry, it can be used as a component of drug molecules for the synthesis of drugs or drug candidates.
-It can also be used for the synthesis of pesticides and the preparation of organic optoelectronic materials.
Preparation Method:
- 5-Cyano-2-fluoropyridine can be synthesized by the reaction of 2-fluoropyridine with sodium cyanide. First, 2-fluoropyridine is reacted with sodium cyanide in an ethanol solvent, followed by dehydration and hydrogenation to finally obtain the target product.
Safety Information:
- 5-Cyano-2-fluoropyridine is stable at room temperature, and its lower melting point and boiling point make it relatively easy to handle.
-in use and storage, should take appropriate chemical operation method and protective measures, avoid contact with skin and eyes, and avoid inhaling its vapor.
-When in contact with strong oxidants and reducing agents, dangerous chemical reactions may occur, and precautions should be taken.
-When handling the compound, follow laboratory safety procedures and wear appropriate personal protective equipment, such as lab gloves and goggles.
Please note that when handling any chemical substances, you should exercise caution and follow safe and compliant operating procedures.
Last Update:2024-04-09 21:01:54