2-Cyanopiperidine
2-Cyanopiperidine
CAS: 42457-10-3
Molecular Formula: C6H10N2
2-Cyanopiperidine - Names and Identifiers
| Name | 2-Cyanopiperidine |
| Synonyms | Pipecolonitrile 2-CYANOPIPERIDINE 2-Cyanopiperidine (S)-2-Cyanopiperidine (S) 2-CYANOPIPERIDINE PIPERIDINE CARBONITRILE 2-piperidinecarbonitrile 2-PIPERIDINECARBONITRILE PIPERIDINE-2-CARBONITRILE Piperidine-2-carbonitrile 2-Piperidinecarbonitrile hydrochloride (S)-N-TERT-BUTOXYCARBONYL-2-CYNOPIPERIDINE |
| CAS | 42457-10-3 |
| EINECS | 212-374-4 |
| InChI | InChI=1/C6H10N2/c7-5-6-3-1-2-4-8-6/h6,8H,1-4H2 |
2-Cyanopiperidine - Physico-chemical Properties
| Molecular Formula | C6H10N2 |
| Molar Mass | 110.16 |
| Density | 0.98±0.1 g/cm3(Predicted) |
| Boling Point | 90-92 °C(Press: 12 Torr) |
| Flash Point | 90.7°C |
| Solubility | Dichloromethane |
| Vapor Presure | 0.082mmHg at 25°C |
| Appearance | Oil |
| Color | Colorless |
| pKa | 6.65±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.475 |
2-Cyanopiperidine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
2-Cyanopiperidine - Introduction
2-Cyanopiperidine is an organic compound with the chemical formula C7H11N and a molecular weight of 109.17g/mol. The following is a description of the nature, use, preparation and safety information of 2-Cyanopiperidine:
Nature:
-Appearance: 2-Cyanopiperidine is a colorless liquid or solid crystal.
-Melting point: 61-62°C
-Boiling Point: 203-204°C
-Density: 1.01 g/mL(25°C)
-Solubility: 2-Cyanopiperidine is soluble in most polar solvents such as ethanol, acetone and dichloromethane.
Use:
-Catalyst: 2-Cyanopiperidine can be used as a catalyst in organic synthesis, such as in the synthesis of amino acids.
-Drug synthesis: It can also be used to synthesize drugs. Compounds containing 2-Cyanopiperidine group usually have certain biological activity.
Preparation Method:
- 2-Cyanopiperidine can be prepared by reacting 2-piperidone with hydrocyanic acid. First, 2-piperidone is reacted with sodium cyanide to form a dicyanide intermediate, and then reacted with hydrocyanic acid to form 2-Cyanopiperidine.
Safety Information:
- 2-Cyanopiperidine may have certain irritation and sensitization to the human body, and attention should be paid to avoiding eyes and skin when contacting.
-When using 2-Cyanopiperidine, good laboratory practices and personal protective measures should be taken, such as wearing gloves, goggles and protective clothing.
-Should be stored in a dry, cool place, away from fire and flammable substances.
Nature:
-Appearance: 2-Cyanopiperidine is a colorless liquid or solid crystal.
-Melting point: 61-62°C
-Boiling Point: 203-204°C
-Density: 1.01 g/mL(25°C)
-Solubility: 2-Cyanopiperidine is soluble in most polar solvents such as ethanol, acetone and dichloromethane.
Use:
-Catalyst: 2-Cyanopiperidine can be used as a catalyst in organic synthesis, such as in the synthesis of amino acids.
-Drug synthesis: It can also be used to synthesize drugs. Compounds containing 2-Cyanopiperidine group usually have certain biological activity.
Preparation Method:
- 2-Cyanopiperidine can be prepared by reacting 2-piperidone with hydrocyanic acid. First, 2-piperidone is reacted with sodium cyanide to form a dicyanide intermediate, and then reacted with hydrocyanic acid to form 2-Cyanopiperidine.
Safety Information:
- 2-Cyanopiperidine may have certain irritation and sensitization to the human body, and attention should be paid to avoiding eyes and skin when contacting.
-When using 2-Cyanopiperidine, good laboratory practices and personal protective measures should be taken, such as wearing gloves, goggles and protective clothing.
-Should be stored in a dry, cool place, away from fire and flammable substances.
Last Update：2024-04-09 02:00:46
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Product Name: 2-Cyanopiperidine Visit Supplier Webpage Request for quotationCAS: 42457-10-3
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Mobile: 18021002903
QQ: 3008007409
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