2-Diisopropylaminoethanol
2-(diisopropylamino)ethanol
CAS: 96-80-0
Molecular Formula: C8H19NO
2-Diisopropylaminoethanol - Names and Identifiers
2-Diisopropylaminoethanol - Physico-chemical Properties
| Molecular Formula | C8H19NO |
| Molar Mass | 145.24 |
| Density | 0.826g/mLat 25°C(lit.) |
| Melting Point | -39 °C |
| Boling Point | 187-192°C(lit.) |
| Flash Point | 158°F |
| Solubility | Chloroform (Soluble), Methanol (Slightly) |
| Vapor Presure | <1 mm Hg ( 20 °C) |
| Vapor Density | 5 (vs air) |
| Appearance | Oil |
| Color | Light Yellow to Yellow |
| BRN | 1697955 |
| pKa | 14.75±0.10(Predicted) |
| Storage Condition | Refrigerator, under inert atmosphere |
| Stability | Stable. Incompatible with acids, strong oxidizing agents. |
| Refractive Index | n20/D 1.442(lit.) |
| Physical and Chemical Properties | Colorless oily liquid, flammable. Freezing point -39.3 ℃, boiling point 191 ℃, relative density 0.8742(20/20 ℃), refractive index 1.4431. Flash point 79 ℃. Slightly soluble in water. |
2-Diisopropylaminoethanol - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R20/22 - Harmful by inhalation and if swallowed. R24 - Toxic in contact with skin R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2922 8/PG 2 |
| WGK Germany | 2 |
| RTECS | KK5950000 |
| FLUKA BRAND F CODES | 9-23 |
| Hazard Class | 3.2 |
| Packing Group | III |
2-Diisopropylaminoethanol - Nature
Open Data Verified Data
colorless oily liquid, flammable. Slightly soluble in water. Relative density 0.8742. Boiling point 191 °c. Flash point 79. Refractive index 4431.
Last Update：2024-01-02 23:10:35
2-Diisopropylaminoethanol - Preparation Method
Open Data Verified Data
diisopropylamine and water are sent to the reaction tank, cooled to 0~5 °c, and ethylene oxide is introduced to react at a temperature of 30~50 °c, and then the reaction solution is subjected to atmospheric distillation, the low boiling matter at 90 °c and the medium boiling matter at 120 °c were removed for recovery and application. Finally, vacuum distillation was carried out, and a fraction of 90-100 ° C. Was cut off at a pressure of 2. 666kPa to obtain a finished product of N,N-isopropylethanolamine.
Last Update：2022-01-01 10:35:29
2-Diisopropylaminoethanol - Use
Open Data Verified Data
for the synthesis of organic chemical products and drugs. It can also be used in the production of fiber additives, emulsifiers and catalysts.
Last Update：2022-01-01 10:35:28
2-Diisopropylaminoethanol - Safety
Open Data Verified Data
- This product is flammable, low toxicity. Production equipment should be closed, the workshop should be ventilated, pay attention to fire prevention. The operator should wear protective gear.
- The glass bottle outer wood box is lined with plastic for packaging, and stored in a cool, dry and ventilated warehouse; Isolation with caustic and oxidant.
Last Update：2022-01-01 10:35:29
2-Diisopropylaminoethanol - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | is used in organic synthesis and is an intermediate of the anticholinergic Bromo-propylamidolin. It can also be used for fiber additives, emulsifiers and catalysts. |
| production method | is obtained by the addition of diisopropylamine and ethylene oxide. Diisopropylamine and water were added to the reaction Pan, cooled to 0-5 °c, and ethylene oxide was introduced. The temperature was naturally raised to 20-30 ℃, stirred for 4H and gradually raised to 40-50 ℃, and then continued for 4H. Left overnight. Next day, the reaction liquid was fractionated under normal pressure, and low boiling matters below 90 ℃ (recovery and application) and medium boiling matters below 120 ℃ (recovery and application) were removed, followed by decompression and fractionation, the 90-100 °c (2.67kPa) fraction was collected as diisopropylaminoethanol. Raw material consumption quota: diisopropylamine 888kg/t, ethylene oxide 293kg/t. |
| category | corrosive article |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 860 mg/kg; Oral-mouse LD50: 770 mg/kg |
| stimulation data | Skin-rabbit 500 mg mild; Eye-rabbit 0.75 mg severe |
| flammability hazard characteristics | flammability |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from alkali and oxidant |
| fire extinguishing agent | carbon dioxide, dry powder |
Last Update：2024-04-10 22:29:15
