2-Ethoxy-3-pyridineboronicacid - Names and Identifiers
2-Ethoxy-3-pyridineboronicacid - Physico-chemical Properties
Molecular Formula | C7H10BNO3
|
Molar Mass | 166.97 |
Density | 1.2g/cm3 |
Boling Point | 334.3°C at 760 mmHg |
Flash Point | 156°C |
Vapor Presure | 5.09E-05mmHg at 25°C |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.517 |
MDL | MFCD06201036 |
2-Ethoxy-3-pyridineboronicacid - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
2-Ethoxy-3-pyridineboronicacid - Introduction
2-Ethypyridine-3-boronic acid is an organic compound with the chemical formula C7H10BNO3.
It has the following properties:
-Appearance is a white crystalline solid;
-Melting point between 95-97 degrees Celsius;
-Soluble in water and organic solvents such as ethanol, dimethyl sulfoxide, etc;
-Stable in air, but may react when encountering strong oxidants.
2-Ethypyridine-3-boronic acid has a wide range of applications in organic synthesis. It is often used as a boronic acid reagent in organic synthesis and can be used to construct carbon-boron bonds. It can react with a substrate that undergoes boric acid activation, such as alcohols, acids, amines, etc., to generate the corresponding boric ester, boric ester, or boric amide compound. These reactions are commonly used in organic synthesis to construct carbon-carbon bonds and carbon-nitrogen bonds.
A number of methods can be used to prepare 2-Ethypyridine-3-boronic acid. A common method of preparation is the reaction of 2-ethoxypyridine with triphenylboronic acid to give 2-Ethypyridine-3-boronic acid. This reaction is usually carried out at ambient temperature using ethanol or ether as a solvent. The resulting product can be crystallized and purified to obtain 2-Ethypyridine-3-boronic acid of high purity.
Regarding safety information, 2-Ethoxyyridine-3-boronic acid is generally relatively safe under normal use conditions, but the following matters still need to be noted:
-Avoid direct contact with skin and eyes when in contact. If in contact, rinse with plenty of water immediately.
-Wear appropriate protective gloves and glasses during operation.
-Avoid inhaling powder or generating dust, and wear appropriate respiratory protection if necessary.
-Store away from open flames and heat sources, and ensure sealed storage to avoid contact with oxidants.
In any chemical operation, you should follow the correct laboratory practice and follow the safe operation guidelines of the relevant chemicals.
Last Update:2024-04-10 22:29:15