2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE

2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE - Names and Identifiers

Name	(6-fluoropyridin-3-yl)methanol
Synonyms	6-fluoro-3-PyridineMethanol 3-PyridineMethanol,6-fluoro- 3-pyridinemethanol, 6-fluoro- (6-fluoropyridin-3-yl)methanol (6-Fluoro-3-pyridinyl)methanol (6-FLUOROPYRIDIN-3-YL)METHANOL 3-Pyridinemethanol,6-fluoro-(9CI) 6-Fluoro-3-(Hydroxymethyl)Pyridine 2-Fluoro-5-(hydroxymethyl)pyridine 2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE 2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE(WXFC0734)
CAS	39891-05-9
InChI	InChI=1/C6H6FNO/c7-6-2-1-5(4-9)3-8-6/h1-3,9H,4H2

2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE - Physico-chemical Properties

Molecular Formula	C6H6FNO
Molar Mass	127.12
Density	1.262±0.06 g/cm3(Predicted)
Boling Point	256.4±25.0 °C(Predicted)
Flash Point	108.842°C
Vapor Presure	0.008mmHg at 25°C
pKa	13.29±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.524

2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE - Risk and Safety

Hazard Class

IRRITANT

2-FLUORO-5-(HYDROXYMETHYL)PYRIDINE - Introduction

(6-fluoropyridin-3-yl)methanol is an organic compound with the chemical formula C6H6FNO, also known as (6-fluoropyridin-3-yl)methanol. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance:(6-fluoropyridin-3-yl) The methanol is white crystal or crystalline powder.
-Melting point: about 55-59°C.
-Boiling point: about 240-242°C.
-Density: 1.29g/cm³.
-Solubility: It has low solubility in water, but is soluble in some organic solvents such as ethanol, methanol and dichloromethane.

Use:
The- (6-fluoropyridin-3-yl)methanol can be used as an intermediate in organic synthesis. It can be used as a starting material or an important intermediate for the preparation of other organic compounds.
-It is also used in the field of medicine and can be used as an important part of drug synthesis and structural modification.

Preparation Method:
There are many methods for preparing (6-fluoropyridin-3-yl)methanol, and commonly used methods include:
-reacting pyridine with boron trifluoride (BF3) to obtain 2-fluoropyridine;
-Then use hydrogen and a catalyst (such as platinum catalyst) to reduce 2-fluoropyridine to (6-fluoropyrin-3-yl) methanol.

Safety Information:
- (6-fluoropyridin-3-yl)methanol is an organic compound with certain toxicity. Contact with eyes, skin and inhalation should be avoided. Personal protective equipment such as protective gloves, goggles and masks should be worn during use.
-During storage and handling, avoid contact with oxidants, strong acids or strong bases to prevent dangerous reactions.
-If taken by mistake or inhaled, seek medical attention immediately and provide the product packaging or label to a doctor for diagnosis and treatment.

Last Update：2024-04-09 02:00:45