2-Fluoro-3-(trifluoromethyl)benzylalcohol

2-Fluoro-3-(trifluoromethyl)benzylalcohol - Names and Identifiers

Name	Fluorotrifluoromethylbenzylalcohol
Synonyms	RARECHEM AL BD 0317 Fluorotrifluoromethylbenzylalcohol 2-FLUORO-3-(TRIFLUOROMETHYL)BENZYL ALCOH 2-Fluoro-3-(trifluoromethyl)benzylalcohol 2-Fluoro-3-(Trifluoromethyl)Benzyl Alcohol 2-FLUORO-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL 2-Fluoro-3-(trifluoromethyl)benzenemethanol [2-Fluoro-3-(trifluoromethyl)phenyl]methanol
CAS	207981-45-1
EINECS	630-698-8
InChI	InChI=1/C8H6F4O/c9-7-5(4-13)2-1-3-6(7)8(10,11)12/h1-3,13H,4H2

2-Fluoro-3-(trifluoromethyl)benzylalcohol - Physico-chemical Properties

Molecular Formula	C8H6F4O
Molar Mass	194.13
Density	1.38g/mLat 25°C(lit.)
Melting Point	24-26°C
Boling Point	211°C(lit.)
Flash Point	228°F
Vapor Presure	0.202mmHg at 25°C
pKa	13.69±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	n20/D 1.451(lit.)
MDL	MFCD00061166

2-Fluoro-3-(trifluoromethyl)benzylalcohol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Class	IRRITANT

2-Fluoro-3-(trifluoromethyl)benzylalcohol - Introduction

It is an organic compound with the chemical formula C8H6F4O.

The following properties are:
-Appearance: Colorless to light yellow oily liquid.
-Solubility: Soluble in organic solvents, such as ethanol, ether and dimethylformamide.
-Melting point and boiling point: The melting point is -4 ° C, and the boiling point is 172-173 ° C.
-Density: About 1.47g/cm³.
-Molecular weight: 206.12g/mol.

The use:
-As an important raw material and intermediate in organic synthesis, it is widely used in drug synthesis, pesticide synthesis and other fields.
-Used as a reducing agent and hydrogenation agent in organic synthesis.

Method of preparation:
There are many preparation methods, common methods include:
-Reaction of 2-fluorophenone with trifluoromethyl alcohol.
-2-fluorophenone is reacted with sodium trifluoromethanesulfonate, and then treated with alkali.

The safety information of:
-is low toxicity. But as a chemical, should follow the general safety practice.
-Contact with skin and eyes may cause irritation and should be avoided.
-During use or storage, keep away from heat sources, open flames and oxidants.

Last Update：2024-04-09 02:00:44