2-Fluoro-4-pyridinecarboxaldehyde
2-Fluoropyridine-4-carboxaldehyde
CAS: 131747-69-8
Molecular Formula: C6H4FNO
2-Fluoro-4-pyridinecarboxaldehyde - Names and Identifiers
| Name | 2-Fluoropyridine-4-carboxaldehyde |
| Synonyms | 2-Fluoropyridine-4-c 2-FLUORO-4-FORMYLPYRIDINE 2-Fluoroisonicotinaldehyde 2-fluoropyridin-4-carbaldehyde 2-Fluoro-4-pyridinecarboxaldehyde 2-FLUOROPYRIDINE-4-CARBOXALDEHYDE 2-Fluoropyridine-4-carboxaldehyde 4-Pyridinecarboxaldehyde,2-fluoro-(9CI) 2-fluoro-3-forMylpyridine-4-carboxylic acid 1-[3,5-bis(trifluoromethyl)phenyl]-2-bromoethanone |
| CAS | 131747-69-8 |
| EINECS | 214-589-6 |
| InChI | InChI=1/C10H5BrF6O/c11-4-8(18)5-1-6(9(12,13)14)3-7(2-5)10(15,16)17/h1-3H,4H2 |
2-Fluoro-4-pyridinecarboxaldehyde - Physico-chemical Properties
| Molecular Formula | C6H4FNO |
| Molar Mass | 125.1 |
| Density | 1.257 g/mL at 25 °C |
| Boling Point | 357-403°C (decomposition) |
| Flash Point | 86℃ |
| Vapor Presure | 0.181mmHg at 25°C |
| pKa | -2.40±0.10(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | n20/D1.512 |
2-Fluoro-4-pyridinecarboxaldehyde - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36/38 - Irritating to eyes and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT, KEEP COLD |
2-Fluoro-4-pyridinecarboxaldehyde - Introduction
2-Fluoropyridine-4-carbaldehyde is an organic compound with the chemical formula C6H4FNO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-Fluoropyridine-4-carbaldehyde is a colorless to light yellow liquid.
-Solubility: It can be dissolved in water and has good solubility in organic solvents.
-Melting point and boiling point: Its melting point is about 20-22°C, and the boiling point is about 153-155°C.
-Stability: 2-fluoropyridine-4-formaldehyde is relatively stable at room temperature.
Use:
-2-fluoropyridine-4-carbaldehyde is often used as an intermediate in organic synthesis. It can be used to synthesize a compound called pyridine-4-carbaldehyde, which is commonly used in organic synthesis reactions.
-It can also be used to prepare pyridine derivatives, such as pyridine-4-methanol, etc.
Preparation Method:
- 2-fluoropyridine -4-carbaldehyde can be prepared by the reaction of 2-fluoropyridine and formaldehyde. Acidic conditions and catalysts may be used during the reaction to aid the reaction.
Safety Information:
- 2-fluoropyridine -4-formaldehyde in the use of the process should comply with the general laboratory safety procedures.
-It may cause irritation when in contact with skin, eyes and mucous membranes. Therefore, wear suitable personal protective equipment such as protective gloves, goggles, or masks when handling compounds.
-When conducting experiments or operations, pay attention to avoid inhaling its vapor. Operate in a well-ventilated area, or use equipment such as explosion-proof hoods to reduce vapor exposure.
-In the event of an accident such as inhalation or skin contact, wash the affected area immediately and seek medical assistance if necessary.
Nature:
-Appearance: 2-Fluoropyridine-4-carbaldehyde is a colorless to light yellow liquid.
-Solubility: It can be dissolved in water and has good solubility in organic solvents.
-Melting point and boiling point: Its melting point is about 20-22°C, and the boiling point is about 153-155°C.
-Stability: 2-fluoropyridine-4-formaldehyde is relatively stable at room temperature.
Use:
-2-fluoropyridine-4-carbaldehyde is often used as an intermediate in organic synthesis. It can be used to synthesize a compound called pyridine-4-carbaldehyde, which is commonly used in organic synthesis reactions.
-It can also be used to prepare pyridine derivatives, such as pyridine-4-methanol, etc.
Preparation Method:
- 2-fluoropyridine -4-carbaldehyde can be prepared by the reaction of 2-fluoropyridine and formaldehyde. Acidic conditions and catalysts may be used during the reaction to aid the reaction.
Safety Information:
- 2-fluoropyridine -4-formaldehyde in the use of the process should comply with the general laboratory safety procedures.
-It may cause irritation when in contact with skin, eyes and mucous membranes. Therefore, wear suitable personal protective equipment such as protective gloves, goggles, or masks when handling compounds.
-When conducting experiments or operations, pay attention to avoid inhaling its vapor. Operate in a well-ventilated area, or use equipment such as explosion-proof hoods to reduce vapor exposure.
-In the event of an accident such as inhalation or skin contact, wash the affected area immediately and seek medical assistance if necessary.
Last Update：2024-04-10 22:29:15
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