Molecular Formula | C9H10F3NO2 |
Molar Mass | 221.18 |
Density | 1.303±0.06 g/cm3(Predicted) |
Melting Point | 93-94 °C(Solv: isopropyl ether (108-20-3); hexane (110-54-3)) |
Boling Point | 273.6±40.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Beige to Light Brown |
pKa | 13.17±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Overview | 2-hydroxymethyl-3-methyl-4-(2,2, 2-trifluoroethoxy) pyridine is an important intermediate for the synthesis of lansoprazole. The existing synthesis method obtains a crude product of 2-hydroxymethyl-3-methyl-4-(2,2, 2-trifluoroethoxy) pyridine, it contains a large amount of impurities such as lansoprazole hydroxyl, which is not conducive to the late synthesis and use of substances, and seriously affects the improvement of product quality. |
application | lansoprazole hydroxyl is an impurity produced in the synthesis of lansoprazole and can be used as a reference substance. |