Name | 2-Amino-4-nitrophenol |
Synonyms | 4-NAP rodol42 nci-c55958 C.I. 76530 p-nitroaminofenol P-NITRO-O-AMINOPHENOL 2-AMINO-4-NITROPHENOL 2-Amino-4-nitrophenol 4-Nitro-2-Aminophenol 2-amino-4-nitrophenolate 2-Hydroxy-5-nitroaniline 3-AMINO-4-HYDROXYNITROBENZENE 3-Amino-4-hydroxynitrobenzene p-Nitro-o-aminophenol 4-Nitro-2-aminophenol |
CAS | 99-57-0 |
EINECS | 202-767-9 |
InChI | InChI=1/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2 |
Molecular Formula | C6H6N2O3 |
Molar Mass | 154.12 |
Density | 1.3617 (estimate) |
Melting Point | 140-143 °C (lit.) |
Boling Point | 322.46°C (rough estimate) |
Flash Point | 100 °C |
Water Solubility | slightly soluble |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0.005Pa at 25℃ |
Appearance | Solid |
Color | Dark Yellow to Brown |
BRN | 776533 |
pKa | 6.82±0.22(Predicted) |
Storage Condition | Refrigerator, Under Inert Atmosphere |
Refractive Index | 1.6890 (rough estima |
Physical and Chemical Properties | Characteristics of Brown yellow or orange crystals. melting point 80~90 ℃ solubility: soluble in acetic acid, ethanol and acetic acid, slightly soluble in water. |
Use | Used as a dye and pharmaceutical intermediates |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R68 - Possible risk of irreversible effects R43 - May cause sensitization by skin contact R40 - Limited evidence of a carcinogenic effect R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. |
UN IDs | 2811 |
WGK Germany | 2 |
RTECS | SJ6300000 |
TSCA | Yes |
HS Code | 29071990 |
Hazard Note | Irritant |
brown or orange Flake crystals. A water melting point of 80~90 deg C, anhydrous melting point of 145~147 deg C (142~143 deg C; 195~198 deg C decomposition). Soluble in acetic acid, ethanol and ether, slightly soluble in water.
dye intermediates, direct dyes and reactive dyes can be synthesized.
LogP | 1.26 |
(IARC) carcinogen classification | 3 (Vol. 57) 1993 |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | for the manufacture of reactive dyes, acid dyes, neutral dyes and Solvent dyes, etc. as dyes and pharmaceutical intermediates. For acid-borne Brown RH; Neutral black BL, BRL, BGL, etc. used as dye and pharmaceutical intermediates as pesticide and pharmaceutical intermediates |
production method | prepared by hydrolysis of 2, 4-dinitrochlorobenzene and partial reduction of sodium polysulfide. Raw material consumption quota: 2, 4-dinitrochlorobenzene (industrial) 2100kg/t, liquid alkali (40%)2050kg/t, sodium polysulfide (100%)700kg/t, hydrochloric acid (37%)150kg/t. |
category | toxic substances |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 2400 mg/kg; Oral-mouse LD50: 850 mg/kg |
stimulation data | eyes-rabbits 100 mg/24 h moderate |
flammability hazard characteristics | open flame flammable; Thermal decomposition of toxic nitrogen oxide gases |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
fire extinguishing agent | carbon dioxide, sand, foam, dry powder |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |