2-Hydroxy-gama-butyrolactone
2-Hydroxy-gama-butyrolactone
CAS: 19444-84-9
Molecular Formula: C4H6O3
2-Hydroxy-gama-butyrolactone - Names and Identifiers
| Name | 2-Hydroxy-gama-butyrolactone |
| Synonyms | AKOS 224 α-Hydroxy-γ-butyrolactone 2-Hydroxy-gama-butyrolactone 2-HYDROXY-GAMMA-BUTYROLACTONE 3-HYDROXYTETRAHYDROFURAN-2-ONE DIHYDRO-3-HYDROXY-2(3H)-FURANONE ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 4,5-Dihydro-3-hydroxy-2(3H)-furanone 4,5-Dihydroxy-3-hydroxy-2(3H)-furanone |
| CAS | 19444-84-9 |
| InChI | InChI=1/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1 |
| InChIKey | FWIBCWKHNZBDLS-UHFFFAOYSA-N |
2-Hydroxy-gama-butyrolactone - Physico-chemical Properties
| Molecular Formula | C4H6O3 |
| Molar Mass | 102.09 |
| Density | 1.309 g/mL at 25 °C (lit.) |
| Boling Point | 133 °C/10 mmHg (lit.) |
| Flash Point | >230°F |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Vapor Presure | 0.00371mmHg at 25°C |
| Appearance | Viscous Liquid |
| Color | Clear colorless to yellow |
| BRN | 80587 |
| pKa | 13.07±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | n20/D 1.468(lit.) |
| Physical and Chemical Properties | Boiling Point: 85 - 90 ℃ |
2-Hydroxy-gama-butyrolactone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29322090 |
2-Hydroxy-gama-butyrolactone - Introduction
Also known as 2-HBL, it is an organic compound. The following is a description of the properties, uses, methods of manufacture and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C4H6O3
-Molecular Weight: 102.09
-Melting point:-45 degrees Celsius
-Boiling point: 209 degrees Celsius
-Density: 1.17 g/mL
-Solubility: Soluble in water, ethanol, chloroform and other organic solvents
Use:
-is widely used in organic synthesis, as an intermediate in the synthesis of a variety of organic compounds
-In the field of medicine, it is used to synthesize some drugs and biologically active compounds
-Can be used as an additive for chemicals such as solvents, surfactants and foaming agents
Method:
-The preparation of-a can be obtained by the hydrogen oxidation reaction of γ-butyrolactone and oxygen in the presence of a catalyst
-In the presence of a catalyst, add γ-butyrolactone to the reactor, then inject an appropriate amount of oxygen, and control the reaction temperature and reaction time to get it
Safety Information:
-irritant to skin, eyes and mucous membranes, rinse with water immediately after contact and seek medical help
-Wear protective gloves, goggles and masks during operation
-Do not inhale or ingest, avoid inhaling its vapor or dust
-Avoid high temperatures and fire sources during storage
Please be sure to comply with relevant safety regulations when using, and maintain good laboratory practice.
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C4H6O3
-Molecular Weight: 102.09
-Melting point:-45 degrees Celsius
-Boiling point: 209 degrees Celsius
-Density: 1.17 g/mL
-Solubility: Soluble in water, ethanol, chloroform and other organic solvents
Use:
-is widely used in organic synthesis, as an intermediate in the synthesis of a variety of organic compounds
-In the field of medicine, it is used to synthesize some drugs and biologically active compounds
-Can be used as an additive for chemicals such as solvents, surfactants and foaming agents
Method:
-The preparation of-a can be obtained by the hydrogen oxidation reaction of γ-butyrolactone and oxygen in the presence of a catalyst
-In the presence of a catalyst, add γ-butyrolactone to the reactor, then inject an appropriate amount of oxygen, and control the reaction temperature and reaction time to get it
Safety Information:
-irritant to skin, eyes and mucous membranes, rinse with water immediately after contact and seek medical help
-Wear protective gloves, goggles and masks during operation
-Do not inhale or ingest, avoid inhaling its vapor or dust
-Avoid high temperatures and fire sources during storage
Please be sure to comply with relevant safety regulations when using, and maintain good laboratory practice.
Last Update：2024-04-09 15:17:54
