(5-Chloro-2-pyrazinyl)methanol is an organic compound with the chemical formula C6H5ClN2O. It is a solid with a white to brown color. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to brown solid
-Solubility: Soluble in alcohol and ketone, slightly soluble in water
Use:
-Drug synthesis:(5-Chloro-2-pyrazinyl)methanol can be used to prepare some drugs, such as antibacterial agents, antiviral agents, etc.
Preparation Method:
The preparation of (5-Chloro-2-pyrazinyl)methanol is usually carried out by the following steps:
1. Place the pyrazine in a reaction flask containing methyl bromide.
2. add hydrogen chloride and react for 10-20 minutes to generate 5-chloropyrazine.
3. Under ice bath conditions, 5-chloropyrazine is reacted with sodium hydroxide and methanol. (5-Chloro-2-pyrazinyl)methanol was obtained.
Safety Information:
- (5-Chloro-2-pyrazinyl)methanol should avoid contact with eyes, skin, and administration.
-Use should be careful to avoid inhaling its dust or vapor.
-Wear appropriate protective gloves and goggles during operation.
-If you come into contact with the compound, flush the affected area quickly with plenty of water and seek medical help.