2-Hydroxycarbazole
2-Hydroxycarbazole
CAS: 86-79-3
Molecular Formula: C12H9NO
2-Hydroxycarbazole - Names and Identifiers
| Name | 2-Hydroxycarbazole |
| Synonyms | 2-carbazolol carbazol-2-ol AURORA KA-4595 9H-CARBAZOL-2-OL 9H-carbazol-2-ol 2-Hydroxycarbazole 2-HYDROXYCARBAZOLE 2-Hydroxy-9H-carbazole QS794 2-HYDROXYCARBAZOLE 2-Hydroxycarbazol (9H-Carbazol-2-ol), |
| CAS | 86-79-3 |
| EINECS | 201-699-7 |
| InChI | InChI=1/C12H9NO/c14-8-5-6-10-9-3-1-2-4-11(9)13-12(10)7-8/h1-7,13-14H |
2-Hydroxycarbazole - Physico-chemical Properties
| Molecular Formula | C12H9NO |
| Molar Mass | 183.21 |
| Density | 1.1261 (rough estimate) |
| Melting Point | 270-273 °C (lit.) |
| Boling Point | 316.88°C (rough estimate) |
| Flash Point | 214.7°C |
| Vapor Presure | 4.78E-08mmHg at 25°C |
| BRN | 135859 |
| pKa | 10.05±0.30(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.5880 (estimate) |
| MDL | MFCD00004962 |
2-Hydroxycarbazole - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. |
| WGK Germany | 2 |
| RTECS | FE6355000 |
2-Hydroxycarbazole - Introduction
2-Hydroxycarbazole (2-Hydroxycarbazole) is an organic compound with the chemical formula C12H9NO, which is a derivative of carbazole. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 2-Hydroxycarbazole is a white to light yellow powder crystal.
2. Solubility: Soluble in organic solvents such as ethanol, chloroform and ether, slightly soluble in water.
3. Melting point: about 210-212°C.
Use:
1. Chemical reagent: 2-Hydroxycarbazole can be used as an important organic synthesis intermediate and is widely used in the synthesis of biologically active compounds.
2. Fluorescent dye: Due to the structural characteristics of 2-Hydroxycarbazole, it can be used as a fluorescent labeling agent for staining and microscopic observation.
Preparation Method:
2-Hydroxycarbazole is generally prepared by the hydrogen oxidation of carbazole. The specific step is to react carbazole with a basic oxidizing agent (such as hydrogen peroxide or benzyl peroxide) to form 2-Hydroxycarbazole.
Safety Information:
1. 2-Hydroxycarbazole is relatively stable under normal use conditions, but contact with fire sources should be avoided.
2. operation should wear protective gloves, protective glasses and laboratory jackets and other personal protective equipment, and pay attention to a well-ventilated laboratory environment.
3. Use, handle, and store 2-Hydroxycarbazole in accordance with safe operating procedures to avoid inhalation, chewing, or swallowing.
4. If you touch your skin or eyes by accident, rinse immediately with plenty of water and seek medical help.
5. Keep the container sealed during storage, away from high temperature, fire and oxidizing agents.
Nature:
1. Appearance: 2-Hydroxycarbazole is a white to light yellow powder crystal.
2. Solubility: Soluble in organic solvents such as ethanol, chloroform and ether, slightly soluble in water.
3. Melting point: about 210-212°C.
Use:
1. Chemical reagent: 2-Hydroxycarbazole can be used as an important organic synthesis intermediate and is widely used in the synthesis of biologically active compounds.
2. Fluorescent dye: Due to the structural characteristics of 2-Hydroxycarbazole, it can be used as a fluorescent labeling agent for staining and microscopic observation.
Preparation Method:
2-Hydroxycarbazole is generally prepared by the hydrogen oxidation of carbazole. The specific step is to react carbazole with a basic oxidizing agent (such as hydrogen peroxide or benzyl peroxide) to form 2-Hydroxycarbazole.
Safety Information:
1. 2-Hydroxycarbazole is relatively stable under normal use conditions, but contact with fire sources should be avoided.
2. operation should wear protective gloves, protective glasses and laboratory jackets and other personal protective equipment, and pay attention to a well-ventilated laboratory environment.
3. Use, handle, and store 2-Hydroxycarbazole in accordance with safe operating procedures to avoid inhalation, chewing, or swallowing.
4. If you touch your skin or eyes by accident, rinse immediately with plenty of water and seek medical help.
5. Keep the container sealed during storage, away from high temperature, fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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