2-Isopropyl-1-isoquinolinone
1(2H)-Isoquinolinone,2-(1-methylethyl)-(9CI)
CAS: 101712-97-4
Molecular Formula: C12H13NO
2-Isopropyl-1-isoquinolinone - Names and Identifiers
2-Isopropyl-1-isoquinolinone - Physico-chemical Properties
| Molecular Formula | C12H13NO |
| Molar Mass | 187.24 |
| Density | 1.106 |
2-Isopropyl-1-isoquinolinone - Introduction
2-Isopropyl-1-hydroxyisoquinoline is an organic compound with a chemical formula of C12H15NO and a molecular weight of 189.26g/mol.
Properties of the compound:
1. Appearance: 2-isopropyl-1-hydroxyisoquinoline is a yellow to brown crystalline powder.
2. melting point: about 141-143 ℃.
3. Solubility: slightly soluble in water, soluble in organic solvents such as ether, chloroform, etc.
2-isopropyl -1-hydroxyisoquinoline main use:
1. Catalyst: The compound can be used as a metal coordination catalyst for organic synthesis reactions, such as reduction, hydrogenation and carbonylation reactions.
2. Industrial application: It can also be used for the synthesis of dyes and dye intermediates, and is widely used in the dye industry.
Preparation method of 2-isopropyl-1-hydroxyisoquinoline:
The preparation method of the compound is more complicated, mainly including the following steps:
1. Acrylate carboxylation: Acrylate is mixed with nitric acid and heated to react to generate carboxylic acid.
2. Esterification of carboxylic acid: Condensation reaction of carboxylic acid with isopropanol to obtain the esterification product.
3. Hydroxylation of the esterification product: The esterification product is reacted with an alcohol base or a sodium alloy to obtain 2-isopropyl-1-hydroxyisoquinoline.
Safety Information for 2-Isopropyl-1-Hydroxyisoquinoline:
The compound has no obvious toxicity to human body at room temperature, but the following safety measures should be paid attention:
1. contact: avoid skin and eye contact, such as contact should immediately rinse with plenty of water.
2 inhalation: avoid inhalation of dust or gas, should be in a well ventilated environment operation.
3. Ingestion: It is forbidden to eat or store in the same place as food.
4. storage: should be stored in a dry, cool, ventilated place, away from fire and oxidant.
5. waste disposal: in accordance with local regulations for disposal, do not dump.
Properties of the compound:
1. Appearance: 2-isopropyl-1-hydroxyisoquinoline is a yellow to brown crystalline powder.
2. melting point: about 141-143 ℃.
3. Solubility: slightly soluble in water, soluble in organic solvents such as ether, chloroform, etc.
2-isopropyl -1-hydroxyisoquinoline main use:
1. Catalyst: The compound can be used as a metal coordination catalyst for organic synthesis reactions, such as reduction, hydrogenation and carbonylation reactions.
2. Industrial application: It can also be used for the synthesis of dyes and dye intermediates, and is widely used in the dye industry.
Preparation method of 2-isopropyl-1-hydroxyisoquinoline:
The preparation method of the compound is more complicated, mainly including the following steps:
1. Acrylate carboxylation: Acrylate is mixed with nitric acid and heated to react to generate carboxylic acid.
2. Esterification of carboxylic acid: Condensation reaction of carboxylic acid with isopropanol to obtain the esterification product.
3. Hydroxylation of the esterification product: The esterification product is reacted with an alcohol base or a sodium alloy to obtain 2-isopropyl-1-hydroxyisoquinoline.
Safety Information for 2-Isopropyl-1-Hydroxyisoquinoline:
The compound has no obvious toxicity to human body at room temperature, but the following safety measures should be paid attention:
1. contact: avoid skin and eye contact, such as contact should immediately rinse with plenty of water.
2 inhalation: avoid inhalation of dust or gas, should be in a well ventilated environment operation.
3. Ingestion: It is forbidden to eat or store in the same place as food.
4. storage: should be stored in a dry, cool, ventilated place, away from fire and oxidant.
5. waste disposal: in accordance with local regulations for disposal, do not dump.
Last Update：2024-04-10 22:29:15
