2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir) - Names and Identifiers
2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir) - Physico-chemical Properties
Molecular Formula | C8H14N2S
|
Molar Mass | 170.28 |
Density | 1.039±0.06 g/cm3(Predicted) |
Boling Point | 230.9±15.0 °C(Predicted) |
Flash Point | 93.429°C |
Vapor Presure | 0.064mmHg at 25°C |
pKa | 8.06±0.10(Predicted) |
Storage Condition | 2-8 ℃, dark |
Refractive Index | 1.523 |
2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir) - Risk and Safety
Risk Codes | R21/22 - Harmful in contact with skin and if swallowed.
R38 - Irritating to the skin
R41 - Risk of serious damage to eyes
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
|
2-Isopropyl-4-(Methylaminomethyl)Thiazole(IntermediateOfRitonavir) - Introduction
1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine is an organic compound with the chemical formula C8H16N2S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow liquid or solid
-Molecular weight: 172.29g/mol
-Boiling Point: 244-248 ° C (anhydrous)
-Density: approx. 0.95g/cm³
-Solubility: Soluble in water and some organic solvents
Use:
- 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine is often used as a reagent in biological research in the laboratory, especially in cell culture and biological microscopy.
-It can also be used to prepare pharmaceutical intermediates and pesticides and other compounds.
Method:
A common method of preparation is by reacting p-thiourea with 2-bromoisopropanol. The specific steps are as follows:
1. Thiourea and 2-bromoisopropanol were added to the reaction flask.
2. The reaction flask is heated to reflux, and the common solvent is ethanol or acetone.
3. During the reaction, control the temperature and reaction time to make the two fully react.
4. After the reaction, cool the solution, the product will be precipitated in the form of solid or liquid.
5. The product is purified and dried to obtain 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine.
Safety Information:
-In handling and storage, should follow the safety procedures.
- 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine is an irritant compound and may cause irritation to the eyes, skin and mucous membranes.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing when in use.
-For accidental contact, rinse immediately with plenty of water and seek medical help if necessary.
Although some information about 1-(2-Isopropylthiazol-4-yl)-N-methyl methanamine has been provided, this does not cover all aspects. When using this compound, please follow the relevant safety instructions to ensure correct and safe handling.
Last Update:2024-04-09 15:17:53