2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE

2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE - Names and Identifiers

Name	4,5-diphenyl-2-methylthiazole
Synonyms	LABOTEST-BB LT01414050 2-METHYL-4,5-DIPHENYLTHIAZOLE 2-Methyl-4,5-Diphenylthiazole 4,5-diphenyl-2-methylthiazole 4,5-DIPHENYL-2-METHYLTHIAZOLE Thiazole, 2-methyl-4,5-diphenyl- 2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE 2-methyl-4,5-diphenyl-1,3-thiazole
CAS	3755-83-7
EINECS	223-161-0
InChI	InChI=1/C16H13NS/c1-12-17-15(13-8-4-2-5-9-13)16(18-12)14-10-6-3-7-11-14/h2-11H,1H3

2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE - Physico-chemical Properties

Molecular Formula	C16H13NS
Molar Mass	251.35
Density	1.147g/cm³
Melting Point	44-50 °C (lit.)
Boling Point	370.2°C at 760 mmHg
Flash Point	174.4°C
Solubility	soluble in Methanol
Vapor Presure	2.4E-05mmHg at 25°C
Appearance	powder to crystal
Color	Light orange to Yellow to Green
Storage Condition	Room Temprature
Refractive Index	1.618

2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 3335
WGK Germany	3

2-METHYL-4,5-DIPHENYL-1,3-THIAZOLE - Introduction

4, is an organic compound whose chemical formula is C17H13NS. The following is a description of its nature, use, preparation and safety information:

Nature:
4, is a solid with a light yellow to yellow crystalline form. It has a slightly aromatic smell. Its melting point is about 163-165 degrees Celsius. It is soluble in solvents such as ethanol, dimethyl sulfoxide and dichloromethane.

Use:
4. It is often used as a precursor for fluorescent probes or fluorescent dyes in organic synthesis. It can detect oxygen concentration and other environmental factors through the change of emission intensity. In addition, it can be used in areas such as cell imaging and analysis in biological research.

Preparation Method:
4, can be synthesized by intermolecular condensation reaction. A common synthetic method is the condensation reaction of methylenedianiline and benzaldehyde in the presence of sodium sulfoxylate (NaHSO3). As the reaction proceeds, the intermediates methylenebis (4,5-diphenylthiazole) and methylenebis (4-phenylthiazole) are produced, followed by oxidation and an acid-catalyzed reaction to form a heterocyclic ring structure, resulting in the final preparation of 4, biphenyl.

Safety Information:
Regarding the toxicity and safety of 4, there is currently no clear data for reference. However, as an organic compound, it should generally be handled in a laboratory environment with appropriate safety precautions, such as wearing chemical safety glasses, gloves, and laboratory atmospheric ventilation devices. During use, pay attention to prevent inhalation, swallowing and contact with skin. In case of accidental contact or eating, seek medical advice or medical attention immediately. Observe relevant safety procedures and standards during handling and storage.

Last Update：2024-04-10 22:29:15