2-Methoxy-4-(n-acetyl-piperazin-1-yl)aniline - Names and Identifiers
2-Methoxy-4-(n-acetyl-piperazin-1-yl)aniline - Physico-chemical Properties
Molecular Formula | C13H19N3O2
|
Molar Mass | 249.31 |
Density | 1.185±0.06 g/cm3(Predicted) |
Melting Point | 131 °C |
Boling Point | 495.4±45.0 °C(Predicted) |
pKa | 7.63±0.10(Predicted) |
Storage Condition | 2-8℃ |
2-Methoxy-4-(n-acetyl-piperazin-1-yl)aniline - Upstream Downstream Industry
2-Methoxy-4-(n-acetyl-piperazin-1-yl)aniline - Introduction
2-methoxy-4-(4-acetylpiperazinyl)aniline (2-methoxy-4-(4-acetylpiperazinyl)aniline) is an organic compound with the chemical formula C14H19N3O2.
Its nature:
-Appearance: 2-methoxy-4-(4-acetylpiperazinyl)aniline is a solid substance.
-Solubility: It can be dissolved in some organic solvents, such as dichloromethane, ethanol and Ether solvents.
Its purpose:
- 2-methoxy-4-(4-acetylpiperazinyl)aniline is one of the intermediates in the preparation of drug CO-1686, CO-1686 is an anti-cancer drug for tumors. 2-methoxy-4-(4-acetylpiperazinyl)aniline is used as an intermediate in the synthesis of CO-1686 for subsequent reactions.
Its preparation method:
The preparation method of 2-methoxy-4-(4-acetylpiperazinyl)aniline is mainly synthesized by the method of organic synthetic chemistry. A common method is to first react 2-methoxy-4-chloroaniline with 4-acetylpiperazine to give 2-methoxy-4-(4-acetylpiperazinyl)aniline.
Safety Information:
because 2-methoxy-4-(4-acetylpiperazinyl)aniline is an organic synthesis intermediate, no special safety measures are required, but the safe operation procedures of chemicals should be followed in the operation process, such as wearing appropriate personal protective equipment, avoid direct contact with skin and eyes, and maintain a well-ventilated laboratory environment. When using and handling 2-methoxy-4-(4-acetylpiperazinyl)aniline, care should be taken to avoid contact with ignition sources and other combustibles. If taken by mistake or inhaled by mistake, seek medical attention immediately. In case of skin contact, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 21:04:16