2-Methoxy-pyrimidin-5-ylamine - Names and Identifiers
2-Methoxy-pyrimidin-5-ylamine - Physico-chemical Properties
Molecular Formula | C5H7N3O
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Molar Mass | 125.13 |
Density | 1.224±0.06 g/cm3(Predicted) |
Melting Point | 119-120 °C(Solv: benzene (71-43-2)) |
Boling Point | 294.4±32.0 °C(Predicted) |
pKa | 2.49±0.22(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
2-Methoxy-pyrimidin-5-ylamine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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HS Code | 29335990 |
2-Methoxy-pyrimidin-5-ylamine - Introduction
2-Methoxypyrimidin-5-amine is an organic compound with the chemical formula C5H7N3O. Its molecular structure contains a methoxy group (-OCH3) and an amino group (-NH2). The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: 2-Methoxypyrimidin-5-amine is a white to yellow crystal with special amino and methoxy functional groups.
-Solubility: Its solubility in water is relatively low, and it can be dissolved in many organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-Stability: It is a stable compound that is not easily degraded under conventional storage conditions.
Use:
-Chemical synthesis intermediate: 2-Methoxypyrimidin-5-amine is an important intermediate, often used in the synthesis of organic compounds and drugs.
-Pesticide manufacturing: It can be used to synthesize certain pesticides such as imidacloprid, phenylpyrimidine, etc.
Preparation Method:
2-Methoxypyrimidin-5-amine can be prepared by the following methods:
-Chlorination of pyrimidine: First, pyrimidine is reacted with an alkaline reagent such as potassium bromide or sodium bromide to obtain pyrimidine bromide, then reacted with methanol to generate 2-methoxypyrimidine, and finally reacted with ammonia to obtain the target product.
Safety Information:
- 2-Methoxypyrimidin-5-amine is a chemical reagent that needs to be properly handled and used in the laboratory in accordance with safe operating procedures.
-It should avoid contact with strong oxidants and strong acids, and avoid inhalation of dust or contact with skin.
Last Update:2024-04-09 21:01:54