Name | 2-Methoxy-1,3-thiazole |
Synonyms | 2-METHOXYTHIAZOLE 2-Methoxythiazole 2-Methoxylthiazole 2-Methoxy thiazole 2-methoxy-thiazole Thiazole, 2-methoxy- 2-Methoxy-1,3-thiazole 2-METHOXY-1,3-THIAZOLE |
CAS | 14542-13-3 |
InChI | InChI=1/C4H5NOS/c1-6-4-5-2-3-7-4/h2-3H,1H3 |
Molecular Formula | C4H5NOS |
Molar Mass | 115.15 |
Density | 1.20 |
Boling Point | 150-151°C(lit.) |
Flash Point | >121°F |
Vapor Presure | 5.29mmHg at 25°C |
pKa | 3.24±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.5150(lit.) |
MDL | MFCD01631143 |
Risk Codes | 10 - Flammable |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
HS Code | 29341000 |
Hazard Class | 3 |
Packing Group | III |
introduction | 2-methoxythiazole is a heterocyclic organic compound with density: 1.20 and boiling point: 150-151°C(lit.), which is an important heterocyclic compound in organic medicinal chemistry. |
application | 2-methoxythiazole is an important heterocyclic compound in organic medicinal chemistry, which can be used as local anesthetic and has anticonvulsant, antiviral, antibacterial and insecticidal effects. |
There are many synthetic methods for preparing | thiazole compounds: thiazole compounds are prepared by solid-phase condensation of ketones, elemental iodine and thiourea; It is proposed to prepare thiazole compounds by the interaction of a-halogenated ketones or halogenated aldehydes and thioamides; A- bromo-4-methoxyphenyl ketone and thiourea were refluxed in tetrahydrofuran for 0.5 hours to obtain thiazole compounds; thiazole compounds were synthesized with iodine and thiourea under microwave irradiation; 2-substituted aminothiazole compounds were prepared by the reaction of 2-Bromo-ethanone and substituted thiourea [1], the reaction formula is shown in the figure below. Fig. 1 reaction formula for synthesis of 2-methoxythiazole |
Use | Used as food essence |