2-Methyl-2-(3-bromopropyl)-1,3-dioxolane
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane
CAS: 24400-75-7
Molecular Formula: C7H13BrO2
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane - Names and Identifiers
| Name | 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane |
| Synonyms | 2-(3-Bromopropyl)-2-methyl-1,3-dioxolane 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane 1,3-Dioxolane, 2-(3-bromopropyl)-2-methyl- |
| CAS | 24400-75-7 |
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane - Physico-chemical Properties
| Molecular Formula | C7H13BrO2 |
| Molar Mass | 209.08 |
| Physical and Chemical Properties | Outside View light yellow to colorless liquid |
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane - Introduction
2-Methyl-2-(3-bromopyl)-1,3-dioxolane is an organic compound with the chemical formula C7H13BrO2. The following is its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Density: approx. 1.369g/cm3
-Melting Point: About -25 ℃
-Boiling point: About 155 ℃
-Solubility: Soluble in organic solvents (such as ether, chlorinated hydrocarbons, etc.), insoluble in water.
Use:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane can be used as a reagent and intermediate in organic synthesis.
-It is widely used in the field of drug synthesis, such as for the synthesis of anti-cancer drugs, antibiotics and antiviral drugs.
Method:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane can be synthesized by the following steps:
1.2-methyl -1, 3-dioxolane and bromopropane are reacted by heating to give 2-(3-bromopropyl)-2-methyl -1, 3-dioxopentanol.
2. Then, 2-(3-bromopropyl)-2-Methyl -1, 3-dioxopentanol is dehydrated under the action of alkali to obtain 2-Methyl-2-(3-bromopyl)-1,3-dioxolane.
Safety Information:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is irritating and contact with skin, eyes and mucous membranes should be avoided.
-During operation and storage, good ventilation conditions are required.
-Wear appropriate protective gloves, goggles and protective clothing when using.
-If ingested or inhaled by mistake, seek medical treatment as soon as possible.
Nature:
-Appearance: colorless liquid
-Density: approx. 1.369g/cm3
-Melting Point: About -25 ℃
-Boiling point: About 155 ℃
-Solubility: Soluble in organic solvents (such as ether, chlorinated hydrocarbons, etc.), insoluble in water.
Use:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane can be used as a reagent and intermediate in organic synthesis.
-It is widely used in the field of drug synthesis, such as for the synthesis of anti-cancer drugs, antibiotics and antiviral drugs.
Method:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane can be synthesized by the following steps:
1.2-methyl -1, 3-dioxolane and bromopropane are reacted by heating to give 2-(3-bromopropyl)-2-methyl -1, 3-dioxopentanol.
2. Then, 2-(3-bromopropyl)-2-Methyl -1, 3-dioxopentanol is dehydrated under the action of alkali to obtain 2-Methyl-2-(3-bromopyl)-1,3-dioxolane.
Safety Information:
- 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is irritating and contact with skin, eyes and mucous membranes should be avoided.
-During operation and storage, good ventilation conditions are required.
-Wear appropriate protective gloves, goggles and protective clothing when using.
-If ingested or inhaled by mistake, seek medical treatment as soon as possible.
Last Update：2024-04-09 02:00:44
