2-Methyl-2-(piperazin-1-yl)propane
N-tert-Butylpiperazine
CAS: 38216-72-7
Molecular Formula: C8H18N2
2-Methyl-2-(piperazin-1-yl)propane - Names and Identifiers
| Name | N-tert-Butylpiperazine |
| Synonyms | 1-T-BUTYLPIPERAZINE N-t-Butylpiperazine N-T-BUTYLPIPERAZINE N-tert-Butylpiperazine N-TERT-BUTYLPIPERAZINE 1-tert-Butylpiperazine 1-(tert-Butyl)piperazine, tech 2-Methyl-2-(piperazin-1-yl)propane Piperazine, 1-(1,1-dimethylethyl)- |
| CAS | 38216-72-7 |
| InChI | InChI=1/C8H18N2/c1-8(2,3)10-6-4-9-5-7-10/h9H,4-7H2,1-3H3 |
2-Methyl-2-(piperazin-1-yl)propane - Physico-chemical Properties
| Molecular Formula | C8H18N2 |
| Molar Mass | 142.24 |
| Density | 0.890±0.06 g/cm3(Predicted) |
| Melting Point | 32-35℃ |
| Boling Point | 85-87℃/22mm |
| Flash Point | 57.2°C |
| Vapor Presure | 0.713mmHg at 25°C |
| Appearance | Low Melting Solid |
| Color | Colorless to yellow |
| pKa | 9.27±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Light, Air & Moisture Sensitive |
| Refractive Index | 1.457 |
2-Methyl-2-(piperazin-1-yl)propane - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Class | 8 |
2-Methyl-2-(piperazin-1-yl)propane - Introduction
N-tert-Butylpiperazine is an organic compound with a chemical formula of C9H20N2 and a piperazine ring and a tert-butyl group in its structure. It is a colorless to pale yellow liquid with a pungent odor.
N-tert-Butylpiperazine has a certain application in the field of medicine. It is often used as an organic synthetic intermediate for the preparation of antipsychotic drugs, antidepressants and antiepileptic drugs. In addition, it is also used as a component of conditioners, lubricants and detergents.
There are many ways to prepare N-tert-Butylpiperazine. One common method is to react 4-aminopiperidine with t-butyl bromide under appropriate conditions to give the product. In addition, it can also be obtained by reacting tert-butyl bromide with 4-chloropiperidine in the presence of sodium carbonate.
For safety information, N-tert-Butylpiperazine may cause irritation when in contact with skin, eyes and respiratory tract. Therefore, it is necessary to wear appropriate protective equipment, such as gloves, goggles and masks, during use. In addition, should be sealed storage, away from the fire and oxidant. If ingested or inhaled, seek medical attention immediately.
N-tert-Butylpiperazine has a certain application in the field of medicine. It is often used as an organic synthetic intermediate for the preparation of antipsychotic drugs, antidepressants and antiepileptic drugs. In addition, it is also used as a component of conditioners, lubricants and detergents.
There are many ways to prepare N-tert-Butylpiperazine. One common method is to react 4-aminopiperidine with t-butyl bromide under appropriate conditions to give the product. In addition, it can also be obtained by reacting tert-butyl bromide with 4-chloropiperidine in the presence of sodium carbonate.
For safety information, N-tert-Butylpiperazine may cause irritation when in contact with skin, eyes and respiratory tract. Therefore, it is necessary to wear appropriate protective equipment, such as gloves, goggles and masks, during use. In addition, should be sealed storage, away from the fire and oxidant. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-09 20:52:54
