2-Methyl-5-Methoxyindole - Names and Identifiers
2-Methyl-5-Methoxyindole - Physico-chemical Properties
Molecular Formula | C10H11NO
|
Molar Mass | 161.2 |
Density | 1.0840 (rough estimate) |
Melting Point | 86-88 °C (lit.) |
Boling Point | 145 °C / 1.5mmHg |
Flash Point | 113.1°C |
Solubility | Soluble in methanol (very faint turbidity.) |
Vapor Presure | 0.00123mmHg at 25°C |
Appearance | White to light yellow to tan powder or crystal |
Color | White to light beige |
pKa | 17.28±0.30(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.5200 (estimate) |
MDL | MFCD00005620 |
2-Methyl-5-Methoxyindole - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
HS Code | 29339900 |
Hazard Class | IRRITANT |
2-Methyl-5-Methoxyindole - Introduction
5-methoxy-2-methylindole is an organic compound with the chemical formula C11H11NO.
Nature:
1. Appearance: 5-methoxy -2-methyl indole is a white crystalline solid.
2. Solubility: It is soluble in common organic solvents, such as ethanol, dimethyl sulfoxide, etc.
3. melting point: its melting point is 86-89 degrees Celsius.
4. Stability: It is relatively stable at room temperature, but should avoid exposure to light and air to avoid decomposition and oxidation.
Use:
5-methoxy-2-methylindole is commonly used in the field of organic synthesis, as intermediates or raw materials, to participate in the synthesis of other compounds, such as fluorescent dyes, pharmaceutical intermediates. It can also be used to study the synthesis and application of active compounds.
Preparation Method:
The preparation of 5-methoxy-2-methylindole can be carried out by the following reaction:
1. First, 2-methylindole is reacted with methyl iodide to obtain 2-methyl-5-methoxyindole.
2. 2-Methyl-5-methoxyindole is then treated with an alkali alcohol solution to obtain 5-methoxy-2-methylindole.
Safety Information:
1. The allergenicity of 5-methoxy-2-methylindole is unknown. Direct contact with skin and inhalation should be avoided.
2. in the process of operation, should wear appropriate protective measures, such as gloves and goggles, etc.
3. If exposed or inhaled, immediately remove from fresh air and seek medical attention.
Last Update:2024-04-09 21:01:54