2-Morpholine-4,6-dichloropyriMidine

2-Morpholine-4,6-dichloropyriMidine - Names and Identifiers

Name	4-(4,6-Dichloropyrimidin-2-yl)morpholine
Synonyms	T6N DOTJ A- BT6N CNJ DG FG 2-Morpholine-4,6-dichloropyriMidine 2-Morpholino-4,6-dichloropyrimidine 4,6-dichloro-2-MorpholinopyriMidine 4-(4,6-Dichlorpyrimidin-2-yl)morpholin 4-(4,6-Dichloro-2-pyriMidyl)Morpholine 2-(4-Morpholino)-4,6-dichloropyrimidine 4-(4,6-Dichloropyrimidin-2-yl)morpholine 4-(4,6-Dichloropyrimidin-2-yl)-morpholine morpholine, 4-(4,6-dichloro-2-pyrimidinyl)-
CAS	10397-13-4
InChI	InChI=1/C8H9Cl2N3O/c9-6-5-7(10)12-8(11-6)13-1-3-14-4-2-13/h5H,1-4H2
InChIKey	OXCOCPRVQUEIOL-UHFFFAOYSA-N

2-Morpholine-4,6-dichloropyriMidine - Physico-chemical Properties

Molecular Formula	C8H9Cl2N3O
Molar Mass	234.08
Density	1.435±0.06 g/cm3(Predicted)
Melting Point	139.0 to 143.0 °C
Boling Point	392.9±52.0 °C(Predicted)
Flash Point	191.425°C
Vapor Presure	0mmHg at 25°C
Appearance	White to white-like solid
pKa	-1.07±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.577
MDL	MFCD05022359

2-Morpholine-4,6-dichloropyriMidine - Risk and Safety

HS Code

29349990

2-Morpholine-4,6-dichloropyriMidine - Introduction

2-Morpholino-4, 6-dichloropyrimidine, also commonly known as 2-MDP, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:

Nature:
2-morpholino-4, 6-dichloropyrimidine is a solid compound with a chemical formula of C7H6Cl2N2 and a relative molecular mass of 177.04g/mol. It has the appearance of white to yellow crystals and its melting point is between 120-125°C. It has low solubility in water, but has good solubility in organic solvents such as alcohols and ketones.

Use:
2-morpholino-4, 6-dichloropyrimidine has a wide range of applications in the field of medicine. It is often used as a pharmaceutical intermediate for the preparation of various drugs. It is widely used in the synthesis of anti-cancer drugs and anti-metabolic disease drugs. It can also be used in cosmetics and personal care products.

Preparation Method:
The preparation of 2-morpholinyl-4, 6-dichloropyrimidine can be obtained by the reaction of 2-morpholinecarboxaldehyde and 2-chloro-4, 6-dinitropyrimidine. Specific synthetic methods can be further referred to the organic chemical synthesis manual.

Safety Information:
2-Morpholino-4, 6-dichloropyrimidine is generally relatively safe under normal conditions of use. However, as an organic compound, exposure to it may cause irritation. Appropriate protective measures such as gloves and goggles should be worn during handling. When stored, it should be kept in a closed container and away from fire and oxidizing agents. If taken by mistake or inhaled by mistake, seek medical attention immediately.

Last Update：2024-04-09 20:45:29