2-NITROANISOL
2-Nitroanisole
CAS: 91-23-6
Molecular Formula: C7H7NO3
2-NITROANISOL - Names and Identifiers
| Name | 2-Nitroanisole |
| Synonyms | 2-NITROANISOL 2-NITROANISOLE 2-Nitroanisole o-NitroAnisole o-Nitro Anisole Anisole, o-nitro- 2-METHOXYNITROBENZENE 2-Methoxynitrobenzene l-Methoxy-2nitrobenzene 1-methoxy-2-nitrobenzene 1-methoxy-2-nitro-benzen 1-Nitro-2-methoxybenzene 1-METHOXY-2-NITROBENZENE 2-Methoxy-1-nitrobenzene |
| CAS | 91-23-6 |
| EINECS | 202-052-1 |
| InChI | InChI=1/C6H5NO2.C2H6O/c8-7(9)6-4-2-1-3-5-6;1-3-2/h1-5H;1-2H3 |
2-NITROANISOL - Physico-chemical Properties
| Molecular Formula | C7H7NO3 |
| Molar Mass | 153.14 |
| Density | 1.254 g/mL at 25 °C (lit.) |
| Melting Point | 9-12 °C (lit.) |
| Boling Point | 273 °C (lit.) |
| Flash Point | >230°F |
| Water Solubility | 1.45 g/L (20 ºC) |
| Solubility | alcohol: soluble(lit.) |
| Appearance | Oil |
| Specific Gravity | 1.254 |
| Color | Pale Yellow |
| Merck | 14,6584 |
| BRN | 1868032 |
| Storage Condition | Refrigerator, Under Inert Atmosphere |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.561(lit.) |
| Physical and Chemical Properties | Colorless to light yellow flammable liquid. melting point 9.4 ℃ boiling point 277 ℃ relative density 1.2540 refractive index 1.5620 soluble in ethanol and ether, insoluble in water. |
| Use | Used in dye, medicine, perfume and other industries |
2-NITROANISOL - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R45 - May cause cancer R22 - Harmful if swallowed |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2730 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | BZ8790000 |
| TSCA | Yes |
| HS Code | 29093090 |
| Hazard Class | 6.1 |
| Packing Group | III |
2-NITROANISOL - Nature
Open Data Verified Data
colorless to light yellow flammable liquid. The relative density was 1. 2540. Melting point 9.4 °c. Boiling point of 277 deg C (272~273 deg C). Refractive index 5620. Soluble in ethanol and ether, insoluble in water.
Last Update：2024-01-02 23:10:35
2-NITROANISOL - Preparation Method
Open Data Verified Data
O-nitrochlorobenzene and caustic soda, methanol methoxylation reaction to get crude, crude by distillation, washing, drying, to get the finished product.
Last Update：2022-01-01 10:50:30
2-NITROANISOL - Use
Open Data Verified Data
dyes, pharmaceutical intermediates, mainly used for the production of O-amino anisole and the two groups of anisole Amine, red base B, etc.. Can also manufacture cleaning agents.
Last Update：2022-01-01 10:50:30
2-NITROANISOL - Safety
Open Data Verified Data
- This product is toxic. Irritant to the skin, can cause dermatitis, exudative abscess, and can cause human blood poisoning, anesthesia of the central nervous system. Production equipment should be closed, to prevent running, run, drop, leakage phenomenon. The operator should wear protective gear. Have good ventilation.
- it should be packed in iron drum and sealed well. Fireworks should be strictly prohibited in the warehouse. The flammable and toxic substances shall be stored and transported according to the regulations.
Last Update：2022-01-01 10:50:31
2-NITROANISOL - Reference Information
| (IARC) carcinogen classification | 2A (Vol. 65, 127) |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | This product is used in dye, medicine, perfume and other industries, and can be used to manufacture O-amino anisole, n-Anisidine, phenol AS-OL, large red base B, direct lake blue 6B, active soluble blue KD-7G, detergent LS, etc. |
| production method | O-nitrochlorobenzene is methoxylated with caustic soda and methanol to obtain crude product, which is distilled, washed, dried to obtain the finished product. Raw material consumption quota: O-nitrochlorobenzene 1120kg/t, methanol 270kg/t. |
| category | toxic substances |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 740 mg/kg; Oral-mouse LD50: 1300 mg/kg |
| flammability hazard characteristics | flammable in case of open flame; Toxic NOx smoke from combustion |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and food additives |
| fire extinguishing agent | carbon dioxide, foam, sand, water mist |
| Occupational Standard | sel 1 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
