2-Phenylthiazole
2-Phenylthiazole
CAS: 1826-11-5
Molecular Formula: C9H7NS
2-Phenylthiazole - Names and Identifiers
| Name | 2-Phenylthiazole |
| Synonyms | 2-Phenylthiazole 2-PHENYLTHIAZOLE Thiazole, 2-phenyl- 2-Phenyl-1,3-thiazole |
| CAS | 1826-11-5 |
| InChI | InChI=1/C9H7NS/c1-2-4-8(5-3-1)9-10-6-7-11-9/h1-7H |
2-Phenylthiazole - Physico-chemical Properties
| Molecular Formula | C9H7NS |
| Molar Mass | 161.22 |
| Density | 1.17g/ml |
| Melting Point | 114 °C |
| Boling Point | 125-128 °C(Press: 18 Torr) |
| Flash Point | 126.7°C |
| Vapor Presure | 0.00765mmHg at 25°C |
| pKa | 2.43±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.604 |
2-Phenylthiazole - Introduction
2-Phenylthiazole is an organic compound containing a phenyl group and a thiazole group. The following are some of the properties, uses, methods and safety information of 2-Phenylthiazole:
Nature:
-Appearance is white or light yellow crystal.
-Has low solubility, soluble in organic solvents such as ethers, ketones and esters, and insoluble in water.
-Has a strong aromatic odor.
Use:
- 2-Phenylthiazole is widely used in pharmaceutical and agricultural fields.
-In pharmaceuticals, it can be used as an intermediate for the synthesis of active drug molecules, such as anti-cancer drugs and anti-infective drugs.
-In agriculture, it can be used as a raw material for pesticides and fungicides to control pests and germs on crops.
Method:
- 2-Phenylthiazole has many synthesis methods. One commonly used method is to obtain by the reaction of phenyl bromide and sodium thioacetate (or potassium thioacetate).
-During the reaction, the phenyl bromide is added to a mixed solvent of alcohol and water containing sodium thioacetate (or potassium thioacetate), and heated to reflux to finally obtain 2-Phenylthiazole.
Safety Information:
- 2-Phenylthiazole is irritating and should avoid contact with skin and eyes.
-Avoid inhalation and ingestion. If inhaled, immediately move the victim to a place with fresh air and seek medical assistance.
-Appropriate personal protective measures such as gloves, goggles and protective clothing should be taken during handling and storage.
-The compound should be stored and handled properly, avoiding contact with oxidants and strong acids to avoid dangerous substances.
Nature:
-Appearance is white or light yellow crystal.
-Has low solubility, soluble in organic solvents such as ethers, ketones and esters, and insoluble in water.
-Has a strong aromatic odor.
Use:
- 2-Phenylthiazole is widely used in pharmaceutical and agricultural fields.
-In pharmaceuticals, it can be used as an intermediate for the synthesis of active drug molecules, such as anti-cancer drugs and anti-infective drugs.
-In agriculture, it can be used as a raw material for pesticides and fungicides to control pests and germs on crops.
Method:
- 2-Phenylthiazole has many synthesis methods. One commonly used method is to obtain by the reaction of phenyl bromide and sodium thioacetate (or potassium thioacetate).
-During the reaction, the phenyl bromide is added to a mixed solvent of alcohol and water containing sodium thioacetate (or potassium thioacetate), and heated to reflux to finally obtain 2-Phenylthiazole.
Safety Information:
- 2-Phenylthiazole is irritating and should avoid contact with skin and eyes.
-Avoid inhalation and ingestion. If inhaled, immediately move the victim to a place with fresh air and seek medical assistance.
-Appropriate personal protective measures such as gloves, goggles and protective clothing should be taken during handling and storage.
-The compound should be stored and handled properly, avoiding contact with oxidants and strong acids to avoid dangerous substances.
Last Update：2024-04-09 02:00:43
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CAS: 1826-11-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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