2-Propynylchloride
propargyl chloride solution
CAS: 624-65-7
Molecular Formula: C3H3Cl
2-Propynylchloride - Names and Identifiers
2-Propynylchloride - Physico-chemical Properties
| Molecular Formula | C3H3Cl |
| Molar Mass | 74.51 |
| Density | 1.03g/mLat 25°C(lit.) |
| Melting Point | <-50°C |
| Boling Point | 58°C(lit.) |
| Flash Point | 7°F |
| Water Solubility | Not miscible or difficult to mix with water. |
| Solubility | benzene: miscible |
| Vapor Presure | 24.08-69.52kPa at 20-50℃ |
| Appearance | clear liquid |
| Color | Colorless to Red to Green |
| Exposure Limit | ACGIH: TWA 20 ppmOSHA: Ceiling 300 ppm; TWA 200 ppmNIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) |
| Merck | 14,7810 |
| BRN | 506005 |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.456 |
| Physical and Chemical Properties | Flammable, colorless liquid. melting point -78 ℃ boiling point 58 ℃ relative density 1.030 refractive index 1.4350 flash point <15 ℃ solubility insoluble in water, with benzene, toluene, carbon tetrachloride and ethanol, ethyl ether and ethyl acetate miscible. |
| Use | Used in the synthesis of medicine, such as superior drop Ning, can also be used in the system of pesticide soil fumigant |
2-Propynylchloride - Risk and Safety
| Risk Codes | R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R65 - Harmful: May cause lung damage if swallowed R48/20 - R63 - Possible risk of harm to the unborn child |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S27 - Take off immediately all contaminated clothing. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. |
| UN IDs | UN 3286 3/PG 2 |
| WGK Germany | 2 |
| TSCA | Yes |
| HS Code | 29032990 |
| Hazard Class | 3 |
| Packing Group | II |
2-Propynylchloride - Reference Information
Open Data Unverified Data
| LogP | 1.3 at 25℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| purpose | for the synthesis of medicinal products, it can also be used in the preparation of pesticide soil fumigant currently used in the synthesis of electroplating intermediates, pharmaceutical intermediates and pesticide intermediates. It itself is an excellent metal corrosion inhibitor and rust inhibitor. Propargyl is an intermediate of pyrethroid propargyl. used as an intermediate in organic synthesis. It is used in the manufacture of medicine, such as excellent drop Ning and soil fumigant. It is also a modifier of engineering plastics, and its three sodium salt is an excellent heat stabilizer for polyvinyl chloride, and its esters are also important additives for polymers. Anti-inflammatory sulfonamides, used for Staphylococcus, Streptococcus, Pneumonia cocci and meningococcal infections; Allergic to sulfonamides, severe liver and kidney patients should not be used; |
| production method | is obtained by reacting propargyl alcohol with phosphorus trichloride. Firstly, add the Fire oil and phosphorus trichloride into the dry reaction tank, Dropwise add the mixed solution of propargyl alcohol and pyridine below 20 ℃. After adding, heat up to reflux, separate the water layer, add sodium carbonate water window to the oil layer and reach pH = 5-6, separate the water layer, then wash with water, dry, atmospheric pressure distillation, collect 52-60 ℃ fraction to obtain the finished product. Fixed consumption of raw materials: propargyl alcohol (95%)1360kg/t, phosphorus trichloride (96%)1350kg/t. The preparation method is to add phosphorus trichloride and Solvent xylene in the reaction bottle, cool to 0 ℃, Dropwise add propargyl alcohol under stirring, and then warm up to 80 ℃ for reaction, A post-treatment was then performed to obtain the chlorpropyne by distillation. Response equation: HC + C- CH2OH + PCl3 → HC + C- CH2Cl + H3PO3 |
Last Update：2024-04-09 19:43:38
2-Propynylchloride - Nature
Open Data Verified Data
flammable liquid. The relative density was 1. 0297. Melting Point -78 °c. Boiling point of 57 degrees Celsius. Flash point 32. 2-35 °c. Refractive index 4320. Almost insoluble in water, glycerol, and benzene, carbon tetrachloride, ethanol, ethylene glycol, ethyl ether, ethyl acetate miscible.
Last Update：2024-01-02 23:10:35
2-Propynylchloride - Preparation Method
Open Data Verified Data
derived from the interaction of propargyl alcohol with phosphorus trichloride in the presence of pyridine.
Last Update：2022-01-01 10:15:14
2-Propynylchloride - Use
Open Data Verified Data
organic synthesis intermediates, such as for the preparation of medicine, such as the superior drop Ning, can also be used for the preparation of soil fumigant.
Last Update：2022-01-01 10:15:14
2-Propynylchloride - Safety
Open Data Verified Data
- tear. Irritation of the skin. Toxicity was not reported. Should wear protective equipment, avoid direct contact, touch the skin, rinse with a large amount of water. The workplace should be well ventilated and the equipment should be closed.
- it can be bottled and stored in a dark place to prevent fire and heat. The hazardous materials shall be stored and transported according to the regulations.
Last Update：2022-01-01 10:15:15
Supplier List
Spot supply
Product Name: propargyl chloride solution Request for quotationCAS: 624-65-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Multiple Specifications
Product Name: 3-Chloropropyne Request for quotationCAS: 624-65-7
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: propargyl chloride solution Request for quotation
CAS: 624-65-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 624-65-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: propargyl chloride solution Request for quotation
CAS: 624-65-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 624-65-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 3-Chloropropyne Request for quotation
CAS: 624-65-7
Tel:
Email: changlihai_888@163.com
Mobile: 18754361888
QQ: 929843887
Send QQ message
CAS: 624-65-7
Tel:
Email: changlihai_888@163.com
Mobile: 18754361888
QQ: 929843887
Spot supply
Product Name: propargyl chloride solution Request for quotationCAS: 624-65-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Multiple Specifications
Product Name: 3-Chloropropyne Request for quotationCAS: 624-65-7
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: propargyl chloride solution Request for quotation
CAS: 624-65-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 624-65-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: propargyl chloride solution Request for quotation
CAS: 624-65-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 624-65-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 3-Chloropropyne Request for quotation
CAS: 624-65-7
Tel:
Email: changlihai_888@163.com
Mobile: 18754361888
QQ: 929843887Send QQ message
CAS: 624-65-7
Tel:
Email: changlihai_888@163.com
Mobile: 18754361888
QQ: 929843887
View History