2-PyrazineMethanol,5-Methyl- - Names and Identifiers
2-PyrazineMethanol,5-Methyl- - Physico-chemical Properties
Molecular Formula | C6H8N2O
|
Molar Mass | 124.14 |
Density | 1.171±0.06 g/cm3(Predicted) |
Melting Point | 47-48 °C |
Boling Point | 109-112 °C(Press: 0.1 Torr) |
Flash Point | 96.3°C |
Vapor Presure | 0.0272mmHg at 25°C |
pKa | 12.77±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.549 |
2-PyrazineMethanol,5-Methyl- - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
2-PyrazineMethanol,5-Methyl- - Introduction
(5-Methylpyrazin-2-yl)methanol, also known as (5-Methylpyrazin-2-yl)methanol, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid or solid (depending on its form)
-Molecular formula: C7H8N2O
-Molecular weight: 136.15g/mol
-Melting point: about 30-33°C
-Boiling point: about 173-175°C
-Solubility: Soluble in alcohol and ether solvents, slightly soluble in water
Use:
(5-Methylpyrazin-2-yl)methanol has a wide range of applications in organic synthesis, mainly for the following aspects:
-Intermediate in chemical synthesis: As an intermediate in organic synthesis, including the synthesis of heterocyclic compounds and natural products.
-Pharmaceutical field: As an intermediate used in the synthesis of antibacterial agents, anti-inflammatory agents, anti-cancer drugs and other compounds in the pharmaceutical field.
-Pesticide field: used as intermediates and anchoring ligands in pesticide synthesis.
Preparation Method:
There are two main methods for the preparation of
(5-Methylpyrazin-2-yl)methanol:
-Reduction of methyl 2-pyrazinecarboxylate: React methyl 2-pyrazinecarboxylate with a reducing agent (such as hydrogen and a catalyst) to obtain (5-Methylpyrazin-2-yl)methanol.
-Hydroxymethylation reaction of 2-pyrazinecarboxylic acid: 2-pyrazinecarboxylic acid reacts with methanol and an acidic catalyst to generate (5-Methylpyrazin-2-yl)methanol.
Safety Information:
- (5-Methylpyrazin-2-yl) There is no special risk report on the impact of methanol on the human body and the environment at room temperature.
-But as a chemical, please follow the general safety procedures when using, including wearing appropriate protective equipment (such as gloves, safety glasses, etc.), avoid contact with skin and eyes.
-Maintain good ventilation during storage and handling.
-If ingested or inhaled, seek medical attention immediately.
Last Update:2024-04-09 02:00:47