2-Thienyllithium
2-Thienyllithium
CAS: 2786-07-4
Molecular Formula: C4H3LiS
2-Thienyllithium - Names and Identifiers
| Name | 2-Thienyllithium |
| Synonyms | 2-THIENYLLITHIUM 2-Thienyllithium 2-LITHIOTHIOPHENE 2-Thienyllithium solution 2-THIENYLLITHIUM, 1.0M SOLUTION IN TETRA HYDROFURAN |
| CAS | 2786-07-4 |
| EINECS | 220-504-6 |
2-Thienyllithium - Physico-chemical Properties
| Molecular Formula | C4H3LiS |
| Molar Mass | 90.07 |
| Density | 0.829g/mLat 25°C |
| Flash Point | −22°F |
2-Thienyllithium - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14/15 - R19 - May form explosive peroxides R36/37/38 - Irritating to eyes, respiratory system and skin. R67 - Vapors may cause drowsiness and dizziness R65 - Harmful: May cause lung damage if swallowed R62 - Possible risk of impaired fertility R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R48/20 - R40 - Limited evidence of a carcinogenic effect R14 - Reacts violently with water |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 3 |
2-Thienyllithium - Introduction
2-Thienyllithium is an organic compound that contains a thiophene ring and a lithium ion in its molecular structure. The following is a description of the nature, use, formulation and safety information of 2-Thienyllithium:
Properties: 2-Thienyllthickness is a solid compound with a molecular formula of C4H3LiS and a molecular weight of 90.08g/mol. It has the characteristics of strong nucleophilicity and strong alkalinity, and can be dissolved in organic solvents at room temperature, such as ether, dimethylformamide, etc.
Purpose: 2-Thienyllithium is an important reagent commonly used in the field of organic synthesis. It can be used as a nucleophilic reagent with active halogen compounds nucleophilic substitution reaction, resulting in the corresponding 2-thiophene substituted products. In addition, it can also be used as a catalyst or reagent to control or regulate chemical reactions for the synthesis of drugs, materials and other organic compounds.
Preparation Method: The preparation of 2-Thienyllithium is usually carried out by the following steps. First, 2-thiophene and lithium chloride can be reacted in an anhydrous environment to form 2-Thienylllithium. The reaction can be carried out in solution or under a hydrogen atmosphere, and the temperature is often controlled below 0 degrees Celsius. The resulting 2-Thienyllithium can then be obtained by filtration or evaporation of the solvent in the solution.
Safety Information: 2-Thienyllithium is highly alkaline and contact with skin and eyes may cause irritation and burns. Appropriate protective measures, such as gloves, goggles and protective clothing, should be taken during handling and use. In addition, contact with air and water should be avoided during storage to prevent possible reactions and dangers. Disposal shall be carried out in accordance with local regulations to avoid environmental pollution.
Properties: 2-Thienyllthickness is a solid compound with a molecular formula of C4H3LiS and a molecular weight of 90.08g/mol. It has the characteristics of strong nucleophilicity and strong alkalinity, and can be dissolved in organic solvents at room temperature, such as ether, dimethylformamide, etc.
Purpose: 2-Thienyllithium is an important reagent commonly used in the field of organic synthesis. It can be used as a nucleophilic reagent with active halogen compounds nucleophilic substitution reaction, resulting in the corresponding 2-thiophene substituted products. In addition, it can also be used as a catalyst or reagent to control or regulate chemical reactions for the synthesis of drugs, materials and other organic compounds.
Preparation Method: The preparation of 2-Thienyllithium is usually carried out by the following steps. First, 2-thiophene and lithium chloride can be reacted in an anhydrous environment to form 2-Thienylllithium. The reaction can be carried out in solution or under a hydrogen atmosphere, and the temperature is often controlled below 0 degrees Celsius. The resulting 2-Thienyllithium can then be obtained by filtration or evaporation of the solvent in the solution.
Safety Information: 2-Thienyllithium is highly alkaline and contact with skin and eyes may cause irritation and burns. Appropriate protective measures, such as gloves, goggles and protective clothing, should be taken during handling and use. In addition, contact with air and water should be avoided during storage to prevent possible reactions and dangers. Disposal shall be carried out in accordance with local regulations to avoid environmental pollution.
Last Update：2024-04-09 21:01:54
