2-TrifluoroMethyl-4-broMoquinoline

2-TrifluoroMethyl-4-broMoquinoline - Names and Identifiers

Name	4-bromo-2-(trifluoromethyl)quinoline
Synonyms	2-TrifluoroMethyl-4-broMoquinoline 4-bromo-2-(trifluoromethyl)quinoline Quinoline, 4-bromo-2-(trifluoromethyl)- quinoline, 4-bromo-2-(trifluoromethyl)- 4-Bromo-2-(trifluoromethyl)-1-azanaphthalene
CAS	18706-25-7
InChI	InChI=1/C10H5BrF3N/c11-7-5-9(10(12,13)14)15-8-4-2-1-3-6(7)8/h1-5H

2-TrifluoroMethyl-4-broMoquinoline - Physico-chemical Properties

Molecular Formula	C10H5BrF3N
Molar Mass	276.05
Density	1.658
Boling Point	268.9±35.0 °C(Predicted)
Flash Point	116.445°C
Vapor Presure	0.012mmHg at 25°C
pKa	-1.38±0.50(Predicted)
Storage Condition	2-8℃
Refractive Index	1.573

2-TrifluoroMethyl-4-broMoquinoline - Introduction

4-bromo-2-(trifluoromethyl)quinoline, also known as quartz, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4-bromo-2-(trifluoromethyl)quinoline is a colorless crystal or light yellow solid.
-Solubility: It is soluble in common organic solvents, such as ethanol, ether and dichloromethane.
-Melting point: Its melting point is about 80-85 degrees Celsius.
-Boiling point: Its boiling point is about 296 degrees Celsius.
-Chemical properties: The compound is stable to heat and light, and is relatively stable under acidic and alkaline conditions. It can be used as a reagent in the synthesis of aromatic compounds.

Use:
-Chemical synthesis: 4-bromo-2-(trifluoromethyl)quinoline can be used as an important intermediate in organic synthesis. It can be used to synthesize pharmaceutically active or other organic compounds.
-Drug development: It has important application potential in the field of medicine and can be used to develop new drugs or improve existing drugs.
-Pesticide: This compound can also be used for the development and preparation of pesticides.

Method:
-Generally, the preparation method of 4-bromo-2-(trifluoromethyl)quinoline is obtained by acylation of 3-bromobenzoylformate with fluoroacetic acid. The reaction is carried out under appropriate conditions, and usually a solvent and a catalyst are used to promote the reaction.

Safety Information:
-Due to the lack of sufficient toxicity assessment data, the information on toxicity and safety is not complete.
-During handling and use, follow appropriate laboratory practices and take necessary personal protective measures, such as wearing gloves, safety glasses and protective clothing.
-During storage, store in a sealed container to avoid contact with oxygen, fire or combustibles.

Last Update：2024-04-09 21:04:16