2-Vinylpyridine
2-Vinylpyridine
CAS: 100-69-6
Molecular Formula: C7H7N
2-Vinylpyridine - Names and Identifiers
| Name | 2-Vinylpyridine |
| Synonyms | 2VP 2-vinylpiridine 2-VINYLPYRIDINE 2-vinyl-pyridin 2-Vinylpyridine 2-Ethenylpyridine 2-Pyridylethylene 2-ethenyl-pyridin 2-vinylpyridine monomer |
| CAS | 100-69-6 |
| EINECS | 202-879-8 |
| InChI | InChI=1/C7H7N/c1-2-7-5-3-4-6-8-7/h2-6H,1H2 |
| InChIKey | KGIGUEBEKRSTEW-UHFFFAOYSA-N |
2-Vinylpyridine - Physico-chemical Properties
| Molecular Formula | C7H7N |
| Molar Mass | 105.14 |
| Density | 0.975 g/mL at 25 °C(lit.) |
| Melting Point | -50 °C |
| Boling Point | 79-82°C29mm Hg(lit.) |
| Flash Point | 116°F |
| Water Solubility | 2.5 g/100 mL (20 ºC) |
| Solubility | 27g/l |
| Vapor Presure | 10 mm Hg ( 44.5 °C) |
| Appearance | Liquid |
| Color | Clear brown |
| BRN | 104505 |
| pKa | pK1:4.98(+1) (25°C) |
| PH | 8 (100g/l, H2O, 20℃) |
| Storage Condition | Store at -20°C. |
| Stability | Unstable; may be stabilized with a small amount of ter-butyl catechol. Heat sensitive - store cold. Flammable. Incompatible with strong oxidizing agents, strong bases, strong acids. |
| Explosive Limit | 1.3-10.7%(V) |
| Refractive Index | n20/D 1.549(lit.) |
| Physical and Chemical Properties | character colorless liquid. |
| Use | Mainly used for the synthesis of styrene-butadiene rubber latex, also used for the manufacture of Crestor, Betadine hydrochloride and other drugs |
2-Vinylpyridine - Risk and Safety
| Risk Codes | R10 - Flammable R20 - Harmful by inhalation R25 - Toxic if swallowed R34 - Causes burns R42/43 - May cause sensitization by inhalation and skin contact. R36 - Irritating to the eyes R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R43 - May cause sensitization by skin contact R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S16 - Keep away from sources of ignition. S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S28A - S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3073 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | UU1040000 |
| FLUKA BRAND F CODES | 8-19 |
| TSCA | Yes |
| HS Code | 29333999 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | II |
| Toxicity | LD50 orally in Rabbit: 100 mg/kg |
2-Vinylpyridine - Nature
Open Data Verified Data
colorless liquid. Boiling point of 159~160 deg C, 79~82 deg C (3.8663kPa). The relative density (d20) was 0. 9985. Refractive index 1.5495. Flash point 46 degrees Celsius. Very soluble in ethanol, ether, chloroform, soluble in benzene, acetone, water-soluble.
Last Update：2024-01-02 23:10:35
2-Vinylpyridine - Preparation Method
Open Data Verified Data
2 Hydroxyethyl pyridine dehydration process 2-hydroxyethyl pyridine, sodium hydroxide into the dehydration pot, slowly heated to 95~100 deg C, heat preservation reaction 2H, cooling to 40 deg C, add sodium hydroxide for dehydration; Separate water layer, oil layer vacuum distillation, collect 60~75 deg C (2. 27kPa) fraction, 2 A vinyl pyridine.
Last Update：2022-01-01 10:53:15
2-Vinylpyridine - Use
Open Data Verified Data
and butadiene, Styrene copolymerization, made of vinyl pyridine modified latex. It can also be used as a binding agent, and an intermediate for preparing drugs such as silicapine and pethidine.
Last Update：2022-01-01 10:53:14
2-Vinylpyridine - Safety
Open Data Verified Data
- vinyl pyridine has strong tear, irritation and toxicity. The production workshop should be well ventilated and the equipment should be closed. Operators should wear protective equipment (such as wearing gas masks, gloves, wearing work clothes, etc.).
- tightly sealed in glass bottles, external use of iron drum or barrel packaging. Store in a cool, dry and ventilated place. Sun protection, moisture-proof. According to the provisions of the storage and transportation of toxic chemicals.
Last Update：2022-01-01 10:53:15
2-Vinylpyridine - Reference Information
| LogP | 1.54 at 25℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| purpose | mainly used for the synthesis of styrene-butadiene pyridine latex, also used for the manufacture of grams silicon flat, betadine hydrochloride and other drugs The product with butadiene, Styrene copolymerization can be made into vinyl pyridine modified latex, also used as a binder. The oxidation of poly (2-vinylpyridine) yields the drug crezapine, which prevents silicosis; This product is also an intermediate of the vasodilator, peroxidine hydrochloride. Also used for photographic film Halo-free layer and polymer electrolyte. organic synthesis, pharmaceutical synthesis intermediates, can be used for the synthesis of styrene-butadiene pyridine latex, also used for the manufacture of grams Silicon (treatment of silicosis drugs), accompanied by the use of hydrochloric acid (vasodilator), ion exchange resin, chemical film, etc. 2-vinylpyridine is copolymerized with butadiene and styrene to make vinyl pyridine-modified latex, which is also used as a binder. The oxidation of poly (2-vinylpyridine) yields the drug crezapine, which prevents silicosis; This product is also an intermediate of the vasodilator, peroxidine hydrochloride. Also used for photographic film Halo-free layer and polymer electrolyte. |
| production method | obtained by dehydration of 2-hydroxyethyl pyridine. |
| category | flammable substances |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50: 100 mg/kg; Oral-mouse LD50: 420 mg/kg |
| flammability hazard characteristics | open flame flammable; Thermally decomposed toxic nitrogen oxide gas |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| extinguishing agent | dry powder, carbon dioxide, sand, foam |
| spontaneous combustion temperature | 440°C |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 19:55:45
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Product Name: 2-Vinylpyridine Request for quotation
CAS: 100-69-6
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CAS: 100-69-6
Tel: 17505222756
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