2-amino-2-hydroxydiethylsulphite

2-amino-2-hydroxydiethylsulphite - Names and Identifiers

Name	2-[(2-aminoethyl)thio]ethan-1-ol
Synonyms	2-(2-AMINOETHYLTHIO)ETHANOL 2-((2-Aminoethyl)thio)ethanol 2-Amino-2-hydroxydiethylsulfit 2-AMINO-2-HYDROXYDIETHYLSULFIDE 2-[(2-aminoethyl)thio]ethan-1-ol 2-amino-2-hydroxydiethylsulphite 2-[(2-AMINOETHYL)THIO]ETHAN-1-OL 2-(2-Amino-ethylsulfanyl)-ethanol 2-[(2-aminoethyl)sulfanyl]ethanol 2-Aminoethyl-2-hydroxyethyl sulfide
CAS	24304-84-5
EINECS	246-142-9
InChI	InChI=1/C4H11NOS/c5-1-3-7-4-2-6/h6H,1-5H2

2-amino-2-hydroxydiethylsulphite - Physico-chemical Properties

Molecular Formula	C4H11NOS
Molar Mass	121.2
Density	1.104±0.06 g/cm3(Predicted)
Melting Point	3°C
Boling Point	221°C
Flash Point	112.3°C
Vapor Presure	0.00158mmHg at 25°C
Specific Gravity	1.12
pKa	pK1: 9.27(+1) (25°C)
Storage Condition	Room Temprature
Refractive Index	1.525

2-amino-2-hydroxydiethylsulphite - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	2735

2-amino-2-hydroxydiethylsulphite - Introduction

2-[(2-aminoethyl)thio]ethan-1-ol, also known as 2-[(2-aminoethyl)thio]ethan-1-ol, is an organic compound. The following is a description of its properties, uses, preparation methods and safety information:

Nature:
-Appearance: 2-[(2-aminoethyl)thio]ethan-1-ol is a colorless to pale yellow liquid.
-Smell: Has a special smell.
-Melting point: About -35 ℃.
-Boiling point: About 125 ℃.
-Density: about 1.01g/cm³.
-Solubility: Soluble in water, alcohols and Ether solvents.

Use:
- 2-[(2-aminoethyl)thio]ethan-1-ol are widely used in the field of organic synthesis. It can act as a reducing agent, buffer and ligand.
-In the pharmaceutical field, it can be used to synthesize drug intermediates, such as the synthesis of anti-cancer drugs.

Method:
- 2-[(2-aminoethyl)thio]ethan-1-ol can be prepared by the following steps:
1. Reacting dichloroethanol with sulfuric acid to obtain chloroethanol sulfate;
2. Under alkaline conditions, reacting chloroethanol sulfate with 2-aminoethanol to generate ethylamine sulfate;
3. Finally, a reduction reaction was carried out to obtain 2-[(2-aminoethyl)thio]ethan-1-ol.

Safety Information:
- 2-[(2-aminoethyl)thio]ethan-1-ol is irritating and may cause eye, skin and respiratory tract irritation.
-Wear appropriate personal protective equipment such as gloves, glasses and protective clothing when used.
-Avoid inhaling or touching the skin. In case of contact, rinse immediately with clean water.
-Avoid contact with oxidants and strong acids during storage and handling.
-When using and handling, please follow the safety operation procedures and dispose of the waste items in accordance with relevant regulations.

Last Update：2024-04-09 02:00:44