2-amino-4-(ethoxycarbonyl)pyridinium

2-amino-4-(ethoxycarbonyl)pyridinium - Names and Identifiers

Name	2-AMINO-ISONICOTINIC ACID ETHYL ESTER
Synonyms	ETHYL 2-AMINOISONICOTINATE Ethyl 2-aminoisonicotinate 2-amino-4-ethoxycarbonyl-pyridine ETHYL 2-AMINO-4-PYRIDINECARBOXYLATE ETHYL 2-AMINOPYRIDINE-4-CARBOXYLATE 2-amino-4-(ethoxycarbonyl)pyridinium 2-Aminoisonicotinic acid ethyl ester 2-AMINO-ISONICOTINIC ACID ETHYL ESTER 2-Amino-isonicotinic acid methyl ester
CAS	13362-30-6
InChI	InChI=1/C8H10N2O2/c1-2-12-8(11)6-3-4-10-7(9)5-6/h3-5H,2H2,1H3,(H2,9,10)
InChIKey	XVBZFXZNJAFCHL-UHFFFAOYSA-N

2-amino-4-(ethoxycarbonyl)pyridinium - Physico-chemical Properties

Molecular Formula	C8H10N2O2
Molar Mass	166.18
Density	1.192±0.06 g/cm3(Predicted)
Melting Point	123.5-123.6°C
Boling Point	307.2±22.0 °C(Predicted)
Flash Point	139.604°C
Water Solubility	Slightly soluble in water.
Vapor Presure	0.001mmHg at 25°C
Appearance	Solid
Color	Off-white
pKa	4.97±0.11(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.559
MDL	MFCD03791260

2-amino-4-(ethoxycarbonyl)pyridinium - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29333990
Hazard Class	IRRITANT

2-amino-4-(ethoxycarbonyl)pyridinium - Introduction

Ethyl 2-aminoisonicotinate is an organic compound with the chemical formula C7H10N2O2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Ethyl 2-aminoisonicotinate is a colorless to pale yellow liquid.
-Solubility: It is soluble in water and common organic solvents, such as ethanol, ether and dichloromethane.
-Melting point and boiling point: The melting point of 2-aminoisonicotinic acid ethyl ester is about 50-52°C, and the boiling point is about 211-212°C.
-Chemical properties: It is an oxidizable compound and is easily affected by oxidizing substances.

Use:
-Pharmaceutical field: 2-aminoisonicotinic acid ethyl ester is often used as a starting material in the synthesis of drugs, for example, the synthesis of some anticancer drugs requires the use of 2-aminoisonicotinic acid ethyl ester.
-Research use: It can be used as an intermediate in organic synthesis and used to synthesize other complex organic compounds.

Preparation Method:
-2-Aminoisonicotinic acid ethyl ester can be obtained by the reaction of 2-aminoisonicotinic acid and acetic anhydride. The reaction is generally carried out under acidic conditions.

Safety Information:
-Ethyl 2-aminoisonicotinate is a chemical that should be stored properly to avoid exposure to fire and high temperatures.
-During use, care should be taken to avoid inhalation, ingestion or contact with skin and eyes.
-In case of accidental contact, flush the affected area immediately with plenty of water and seek medical help if necessary.
-Wear appropriate personal protective equipment such as gloves, glasses and breathing masks during operation.

Last Update：2024-04-09 15:17:51