2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one
Nolatrexed
CAS: 147149-76-6
Molecular Formula: C14H12N4OS
2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one - Names and Identifiers
| Name | Nolatrexed |
| Synonyms | NOLA-012 Nolatrexed NOLATREXED Nolatrexed [inn] Nolatrexed fandachem 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)- 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one dihydrochloride |
| CAS | 147149-76-6 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19) |
2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one - Physico-chemical Properties
| Molecular Formula | C14H12N4OS |
| Molar Mass | 284.34 |
| Density | 1.46g/cm3 |
| Melting Point | 301-302° |
| Boling Point | 493.6°C at 760 mmHg |
| Flash Point | 252.3°C |
| Vapor Presure | 6.94E-10mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.747 |
2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one - Introduction
Nolatrexed(Noracodex) is a chemical substance with the chemical name 3-Hydroxy-4-methoxybenzoic acid (acid). The following is a description of the nature, use, formulation and safety information of Nolatrexed:
Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in methanol, ethanol and chloroform, almost insoluble in water
-Molecular formula: C8H8O4
-Molecular weight: 168.15g/mol
Use:
-Pharmaceutical industry: Nolatrexed can be used to synthesize drugs, such as anti-inflammatory drugs and antibacterial drugs.
-Cosmetics industry: Nolatrexed is also widely used in cosmetics and is often used as an ingredient in sunscreens, skin care products and hair care products.
Method:
Nolatrexed can be obtained by the substitution reaction of hydroxylated phenol formic acid (salicylic acid). The specific synthesis method may vary slightly depending on the specific experimental conditions.
Safety Information:
- Nolatrexed is generally considered to be a relatively safe chemical substance, but the following matters should be paid attention to during use:
-Contact: avoid prolonged skin contact, if contact with the skin, should immediately rinse with water.
-Inhalation: A well-ventilated working environment should be maintained to reduce the risk of inhaling dust.
-Consumption: It is forbidden to consume Nolatrexed. If ingested by mistake, you should immediately consult your doctor's advice.
-Environmental impact: Try to avoid the discharge of Nolatrexed into the environment, and dispose of it in accordance with local environmental protection regulations.
In general, when used correctly, Nolatrexed is a relatively safe chemical according to general laboratory safety procedures. However, in the process of use, we should still pay attention to reasonable use and avoid prolonged contact or inhalation.
Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in methanol, ethanol and chloroform, almost insoluble in water
-Molecular formula: C8H8O4
-Molecular weight: 168.15g/mol
Use:
-Pharmaceutical industry: Nolatrexed can be used to synthesize drugs, such as anti-inflammatory drugs and antibacterial drugs.
-Cosmetics industry: Nolatrexed is also widely used in cosmetics and is often used as an ingredient in sunscreens, skin care products and hair care products.
Method:
Nolatrexed can be obtained by the substitution reaction of hydroxylated phenol formic acid (salicylic acid). The specific synthesis method may vary slightly depending on the specific experimental conditions.
Safety Information:
- Nolatrexed is generally considered to be a relatively safe chemical substance, but the following matters should be paid attention to during use:
-Contact: avoid prolonged skin contact, if contact with the skin, should immediately rinse with water.
-Inhalation: A well-ventilated working environment should be maintained to reduce the risk of inhaling dust.
-Consumption: It is forbidden to consume Nolatrexed. If ingested by mistake, you should immediately consult your doctor's advice.
-Environmental impact: Try to avoid the discharge of Nolatrexed into the environment, and dispose of it in accordance with local environmental protection regulations.
In general, when used correctly, Nolatrexed is a relatively safe chemical according to general laboratory safety procedures. However, in the process of use, we should still pay attention to reasonable use and avoid prolonged contact or inhalation.
Last Update：2024-04-09 15:17:52
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CAS: 147149-76-6
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CAS: 147149-76-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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