2-broMo-6-(propan-2-yl)pyridine - Names and Identifiers
2-broMo-6-(propan-2-yl)pyridine - Physico-chemical Properties
Molecular Formula | C8H10BrN
|
Molar Mass | 200.08 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-broMo-6-(propan-2-yl)pyridine - Introduction
2-Bromo-6-isopropylpyridine is an organic compound with the chemical formula C9H13BrN.
Nature:
-Appearance: colorless or light yellow liquid
-Smell: Odor similar to hydrocarbon gas
-Density: Approximately 1.18 g/mL
-Melting point: approx. -13°C
-Boiling point: about 209°C
-Soluble: Soluble in ethanol, chloroform and benzene
Use:
2-Bromo-6-isopropylpyridine has important applications in the field of chemistry, and is often used as a bromine source in organic synthesis reactions. It is often used as a trigger for bromination reactions, which can initiate bromination reactions, cyclization reactions and electrophilic substitution reactions. It is also used in drug synthesis and pesticide development.
Preparation Method:
2-Bromo-6-isopropylpyridine can be synthesized by the following steps:
1. substituted pyridine: pyridine is reacted with bromoalkane added under alkaline conditions to generate 2-bromo -6-substituted pyridine.
2. Isopropylation: The obtained 2-bromo-6-substituted pyridine is reacted with isopropanol under acidic conditions by heating to produce 2-bromo-6-isopropylpyridine.
Safety Information:
-2-Bromo-6-isopropylpyridine is irritating to the skin and eyes, and should be rinsed with plenty of water immediately after contact.
-Wear protective gloves and goggles during use to ensure a well-ventilated working environment.
-Long-term or heavy exposure may cause damage to health, please follow the safety procedures.
-Waste should be disposed of in accordance with local regulations and should not be dumped into water sources or the environment.
Last Update:2024-04-09 02:00:40